Item#: CAL-80A Albumin, Polyclonal anti-Human Affinity Purified (ALB)
Product Info:
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| Product Name: | Albumin, Polyclonal anti-Human Affinity Purified (ALB) |
|---|---|
| Ab Concentration: | Typically 1mg/ml or greater |
| Cat. No: | CAL-80A |
| Form: | Liquid in PBS buffer, pH 7.3 |
| Host: | Chicken |
| Immunogen: | Human Albumin |
| Purity: | Affinity Purified |
| Storage: | 2-8 C |
Polyclonal anti-human albumin Specificity: This antibody shows a single precipition arc against human albumin and the albumin in human serum using immunoelectrophoresis.
Working Dilution: Western Blots, 1 to 1,000-10,000 and ELISA, coating, 1 to 200-500
INQUIRE ON BULK QUANTITIES OVER 100mg of polyclonal anti-human albumin
Inquire on our custom polyclonal antibody production. We can host from any species and cross link to your requirements. Custom Polyclonal antibody concentrations available
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CAL-80A Polyclonal Chicken anti-Human Albumin Affinity Purified
Human Serum Albumin (HSA)(ALB)information
Human serum albumin (HSA)(ALB)is the most abundant protein in human blood plasma. Human Serum Albumin (HSA)(ALB) is produced in the liver. Human serum Albumin (HSA)(ALB) is the main protein of plasma; Human Serum Albumin binds water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin and drugs
Human Serum Albumin (HSA)(ALB) clinical significance: Chronic liver disease such as cirrhosis causes diminished production of albumin and, subsequently, decreased human serum albumin (HSA)(ALB) levels. Malnutrition, severe diarrhea, fever, infection, and inadequate iron intake can also cause low albumin (hypoalbuminemia) without associated liver disease.
Human Serum Albumin (HSA)(ALB) testing: In the healthy kidney, albumin's size and negative electric charge exclude it from excretion in the glomerulus.In some diseases including diabetic nephropathy, a major complication of uncontrolled diabetes where protein(s) can cross the glomerulus. The lost Human Serum Albumin (HSA)(ALB) can be detected by a simple urine test. Depending on the amount of Human Serum Albumin (HSA)(ALB lost, a patient may have normal renal function, microalbuminuria, or albuminuria.
Human Serum Albumin (HSA)(ALB study: Human Albumin binding is a crucial determinant of bilirubin clearance in health and bilirubin toxicity in certain disease states. Affinity of human albumin for bilirubin is not constant, but varies with both human serum albumin concentration and buffer composition.Ref: . Biol. Chem., Vol. 276, Issue 32, 29953-29960, August 10, 2001
Human Serum Albumin article: Atomic structure and chemistry of human serum albumin. REF: Nature 358, 209 - 215 (1992).
Structure and ligand binding properties of human serum albumin(HSA). REF: n Med Bull. 1990 Feb;37(1):57-84
Human Serum Albumin study:Fatty acid binding to human serum albumin: new insights from crystallographic studies. REF: Biochim Biophys Acta. 1999 Nov 23;1441(2-3):131-40
Human Serum Albumin research: Location of high and low affinity fatty acid binding sites on human serum albumin revealed by NMR drug-competition analysis. REF: J Mol Biol. 2006 Aug 11;361(2):336-51
Human Serum Albumin article: Modification of amino acid residues in human serum albumin by myeloperoxidase. REF: Free Radic Biol Med. 2006 Feb 1;40(3):516-25
Human Serum Albumin study:An elevated urinary albumin (ALB) excretion predicts de novo development of renal function impairment in the general population. human urinary albumin (ALB) excretion may prove to be a valuable tool to detect subjects renal failure, REF:Kidney International, Volume 66, Supplement 92, November 2004, pp. S18-S21
Human Serum Albumin (HSA) Research: Understanding the molecular basis for the inhibition of the Alzheimer's abeta-Peptide oligomerization by human serum albumin (ALB). Human serum albumin (HSA) inhibits the formation of amyloid beta-peptide (Abeta) fibrils in human plasma. REF: J Am Chem Soc. 2007 Apr 11;129(14):4282-90. Epub 2007 Mar 17