Item#: 490-20 ALKALINE PHOSPHATASE, Porcine

ALKALINE PHOSPHATASE (ALP)from PORCINE KIDNEY BULK QUANTITIES from 1000kU-5 million unit single lot sizes. Custom purification of alkaline phosphatase from other species is available.Custom buffers for Alkaline Phosphatase available on bulk orders.

Porcine (pig) Alkaline Phosphatase (ALP)UNIT DEFINITION: One unit will convert one micromole of p-nitrophenyl phosphate to p-nitrophenol and phosphate per minute at 37C in the presence of AMP (2-amino-2-methyl-1-propanol) at ph 10.35.

We also offer these Alkaline Phosphatase products:
485-10 Alkaline Phosphatase Human
486-10 Alkaline Phosphatase Human
490-20 Alkaline Phosphatase Porcine
480-20 Alkaline Phosphatase Calf
480-40 Alkaline Phosphatase Calf

Alkaline phosphatase (ALP) is a hydrolase enzyme responsible for removing phosphate groups in the 5- and 3- positions from many types of molecules, including nucleotides, proteins, and alkaloids. In humans, ALP is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. The optimal pH for ALP enzyme activity is pH 10 in standard conditions.

Alkaline phosphatase is used in laboratory tests to diagnose liver disease or monitor its course. An alkaline phosphatase (ALP) test may also be used to evaluate the liver when medications are taken that can damage the liver. Alkaline Phosphatase (ALP) levels can be used to monitor the effectiveness of treatment for Paget's disease.