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Item#: 485-10 ALKALINE PHOSPHATASE Human

$150.00/50 units Quantity

$250.00/100 units Quantity


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Product Name: ALKALINE PHOSPHATASE Human
Activity: Typically >10 u/mg @ 37 C
CAS No: 9001-78-9
Cat. No: 485-10
EC No: 3.1.3.1
Expiration: 1 year
Form: Lyophilized
Protein: Typically >0.5 mg protein/mg
Source: Human Placenta
Storage: -20 C
Synonyms: ALP

HUMAN ALKALINE PHOSPHATASE (ALP) BULK QUANTITIES of human placenta(l) alkaline phosphatase (ALP)from 1000-25000 unit single lot sizes. Custom buffers for alkaline phosphatase (ALP)available. Custom fills for alkaline phosphatase (ALP)available.

Human Alkaline Phosphatase (ALP, Alk Phos) from human placenta UNIT DEFINITION: One unit will convert one micromole of p-nitrophenyl phosphate to p-nitrophenol and phosphate per minute at 37C in the presence of AMP(2-amino-2-methyl-1-propanol) at pH 10.35

Alkaline phosphatase (ALP) (EC 3.1.3.1) is a hydrolase enzyme responsible for removing phosphate groups in the 5- and 3- positions from many types of molecules, including nucleotides, proteins, and alkaloids. In human(s), alkaline phosphatase is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. The optimal pH for the enzyme activity is pH=10 in standard conditions


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Alkaline Phosphatase research: Alkaline phosphatase (ALP)(ALK PHOS)from placenta is characteristic for its stability compared with the other types of mammalian isoenzymes. Phosphatase Ref: Fishman, W. H. 1990. Alkaline phosphatase isozymes: recent process. Clin. Biochem. 23:99-104/phosphatase/alkaline

Alkaline Phosphatase research: Alkaline Phosphatase Predicts Survival in Patients with Metastatic Neuroendocrine Tumors. Alkphos REF: Digestive Diseases and Sciences Volume 51, Number 5, May, 2006/phosphatase/alkaline

Alkaline Phosphatase research:Serum soluble factors induce the proliferation, alkaline phosphatase activity and transforming growth factor-beta signal in osteoblastic cells in the patient with hepatitis C-associated osteosclerosis. Alkaline Phosphatase REF: Exp Clin Endocrinol Diabetes. 2006 Nov;114(10):599-604/phosphatase/alkaline

Alkaline Phosphatase research:The relationship between alkaline phosphatase activity and intracellular lipid accumulation in murine 3T3-L1 cells and human preadipocytes Alkaline Phosphatase REF:Anal Biochem. 2006 Jul 15;354(2):247-54 /phosphatase/alkaline

Alkaline Phosphatase research: Inhibition of growth and increase of alkaline phosphatase activity in cultured human oral cancer cells by all-trans retinoic acid. Alkaline Phosphatase REF: Int J Oral Maxillofac Surg. 2006 Jul;35(7):643-8/phosphatase/alkaline

Alkaline Phosphatase research: Pyrophosphate, Alkaline Phosphatase, and Vascular Calcification. Alkaline Phosphatase REF: Circ Res.2006; 99: e2/phosphatase/alkaline


Alkaline Phosphatase research: The Structure of Nucleotide Pyrophosphatase/ Phosphodiesterase and Implications for Enzyme Evolution in the Alkaline Phosphatase Superfamily Alkaline Phosphatase REF: J Zalatan, T Fenn, A Brunger, D Herschlag - The FASEB Journal, 2006/phosphatase/alkaline

Alkaline Phosphatase research:The use of hepatitis C virus NS3/4A and secreted alkaline phosphatase to quantitate cell–cell membrane fusion mediated by severe acute respiratory syndrome coronavirus S protein and the receptor angiotensin-converting enzyme 2.Alkaline Phosphatase ref:
Analytical Biochemistry, Volume 366, Issue 2, 15 July 2007, Pages 190-196/alkaline/phosphatase

Alkaline Phosphatase research:Activity and stability of alkaline phosphatase (ALP) immobilized onto magnetic nanoparticles (Fe3O4).Alkaline Phosphatase ref:Journal of Biotechnology, 5 July 2007/alkaline/phosphatase

Alkaline Phosphatase research: Culture of osteogenic cells from human alveolar bone: a useful source of alkaline phosphatase.Cell Biology InAlkaline Phosphatase ref:ternational,28 June 2007/alkaline/phosphatase

Alkaline Phosphatase research:Engineered disulfide bonds increase active-site local stability and reduce catalytic activity of a cold-adapted alkaline phosphatase.Alkaline Phosphatase ref:
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, Volume 1774, Issue 6, June 2007, Pages 679-687/alkaline/phosphatase/human

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