Polyclonal anti-human alpha 2 macroglobulin (a2M) procedure Chickens were immunized with highly purified human alpha 2-macroglobulin isolated from human serum. The resulting anti-human alpha 2-macroglobulin (a2M)was solid phase absorbed then affinity purified off an antigen containing immunoabsorbant.
This anti-human alpha 2-macroglobulin (A2M) is suitable for depletion, ELISA and Botting applications.
Western Blots 1:1,000
ELISA coating 1:200-1:500
Bulk Quantities over 100mg of polyclonal anti-human alpha 2 Macroglobulin (A2M)
Inquire on our custom polyclonal antibody production. We can host from any species and cross link to your requirements. Custom Polyclonal antibody concentrations available
What is Human Alpha 2 Macroglobulin?
Human Alpha-2-macroglobulin(A2M)is a large plasma protein found in the blood. Human Alpha-2-macroglobulin (A2M) is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis.
Human Alpha-2-macroglobulin(A2M)levels are increased in nephrotic syndrome, a condition wherein the kidneys start to leak out some of the smaller blood proteins.
Human Alpha-2-macroglobulin (A2M) research: Human Alpha-2-macroglobulin (A2M) is a protease inhibitor and cytokine transporter. Human Alpha-2-macroglobulin (A2M) inhibits many proteases, including trypsin, thrombin and collagenase. Human Alpha-2-macroglobulin (A2M)is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. Human Alpha-2-macroglobulin (A2M) Ref. Nat Genet. 1998 Aug;19(4):357-60/human/a2m/alpha/macroglobulin/polyclonal/antibody