Item#: C2M-80A alpha-2-Macroglobulin, Polyclonal anti-Human affinity Purified (A2M)
Product Info:
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| Product Name: | alpha-2-Macroglobulin, Polyclonal anti-Human affinity Purified (A2M) |
|---|---|
| Ab Concentration: | 1mg/ml |
| Cat. No: | C2M-80A |
| Form: | Liquid in PBS, pH 7.2 |
| Host: | Chicken |
| Immunogen: | Human alpha-2-Macroglobulin |
| Protein Conc:: | Typically greater than 1mg/ml |
| Purity: | Affinity Purified |
| Storage: | 2-4C |
Polyclonal anti-human alpha 2 macroglobulin (a2M) procedure Chickens were immunized with highly purified human alpha 2-macroglobulin isolated from human serum. The resulting anti-human alpha 2-macroglobulin (a2M)was solid phase absorbed then affinity purified off an antigen containing immunoabsorbant.
This anti-human alpha 2-macroglobulin (A2M) is suitable for depletion, ELISA and Botting applications.
Western Blots 1:1,000
ELISA coating 1:200-1:500
Bulk Quantities over 100mg of polyclonal anti-human alpha 2 Macroglobulin (A2M)
Inquire on our custom polyclonal antibody production. We can host from any species and cross link to your requirements. Custom Polyclonal antibody concentrations available
What is Human Alpha 2 Macroglobulin?
Human Alpha-2-macroglobulin(A2M)is a large plasma protein found in the blood. Human Alpha-2-macroglobulin (A2M) is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis.
Human Alpha-2-macroglobulin(A2M)levels are increased in nephrotic syndrome, a condition wherein the kidneys start to leak out some of the smaller blood proteins.
Human Alpha-2-macroglobulin (A2M) research: Human Alpha-2-macroglobulin (A2M) is a protease inhibitor and cytokine transporter. Human Alpha-2-macroglobulin (A2M) inhibits many proteases, including trypsin, thrombin and collagenase. Human Alpha-2-macroglobulin (A2M)is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. Human Alpha-2-macroglobulin (A2M) Ref. Nat Genet. 1998 Aug;19(4):357-60/human/a2m/alpha/macroglobulin/polyclonal/antibody
Human Alpha-2-macroglobulin (A2M) research: Activated alpha(2)-macroglobulin induces cell proliferation and mitogen-activated protein kinase activation by LRP-1 in the J774 macrophage-derived cell line. Human Alpha-2-macroglobulin (A2M) REF: Arch Biochem Biophys. 2007 Apr 1;460(1):100-106/human/a2m/alpha/macroglobulin/polyclonal/antibody
Human Alpha-2-macroglobulin (A2M) research: Incorporation of low molecular weight molecules into alpha(2)-Macroglobulin by nucleophilic exchange. Human Alpha-2-macroglobulin (A2M)REF: Biochem Biophys Res Commun. 2007 Jun 1;357(2):433-8/human/a2m/alpha/macroglobulin/polyclonal/antibody
Human Alpha-2-macroglobulin (A2M) research:Functional duplication of ligand-binding domains within low-density lipoprotein receptor-related protein for interaction with receptor associated protein, alpha 2-macroglobulin, factor IXa and factor VIII. Human Alpha-2-macroglobulin (A2M) resf: Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, Volume 1774, Issue 6, June 2007, Pages 714-722/human/a2m/alpha/macroglobulin/polyclonal/antibody
Human Alpha-2-macroglobulin (A2M) research:Activated alpha2-macroglobulin induces cell proliferation and mitogen-activated protein kinase activation by LRP-1 in the J774 macrophage-derived cell line.Human Alpha-2-macroglobulin (A2M) ref:Archives of Biochemistry and Biophysics, Volume 460, Issue 1, 1 April 2007, Pages 100-106//human/a2m/alpha/macroglobulin/polyclonal/antibody
Human Alpha-2-macroglobulin (A2M) research:Roles for C3 and alpha-2 macroglobulin in the transportation and activation of MASP-2 in normal human serum.Human Alpha-2-macroglobulin (A2M) ref:Molecular Immunology, Volume 44, Issues 1-3, January 2007, Page 15/human/a2m/alpha/macroglobulin/polyclonal/antibody