Item#: 108-10 ARGINASE Bovine
Product Info:
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| Product Name: | ARGINASE Bovine |
|---|---|
| Activity: | >10 u/mg at 37C |
| Appearance: | Green-tan powder |
| CAS No: | 9000-96-8 |
| Cat. No: | 108-10 |
| EC No: | 3.5.3.1 |
| Expiration: | 1 year |
| Form: | Lyophlized |
| Protein: | >0.4 mg Protein/mg |
| Source: | Bovine Liver |
| Storage: | -20 C |
| Synonyms: | L-Arginine amidinase,L-Arginine amidino-hydrolase |
Bovine Liver L-Arginase is made to order. Minimum order is 250kU. single lot sizes of bovine liver L-Arginase up to 2000kU.
Arginase deficiency is thought to be the least common of the urea cycle disorders. This entity also manifests itself in a fashion somewhat different from other disorders in the group (see Physical). Two separate isozymes of the enzyme arginase have been reported. Type I is found in the liver and contributes the vast majority of hepatic arginase activity, whereas type II is inducible and found in extrahepatic tissues. The disease is caused by a deficiency of arginase type I in the liver.Arginase Ref: Karl S Roth, MD, Chair, Professor, Department of Pediatrics, Creighton University School of Medicine, July 2007 Emedicine
Unit Definition: One unit will convert 1.0 micromoles of L-Arginase to ornithine and urea per minute at pH 9.5 and 37C
Arginase research:Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy.Arginase ref: Eur J Immunol. 2007 Apr;37(4):935-45/arginase.
Arginase research:Arginase, Prostaglandins, and Myeloid-Derived Suppressor Cells in Renal Cell Carcinoma. Arginase ref:Clinical Cancer Research 13, 721s-726s, January 15, 2004/arginase.
Arginase research:Microcalorimetric studies on the non-competitive inhibition of bovine liver arginase.Arginase ref:Journal of Thermal Analysis and Calorimetry Volume 77, Number 3 / September, 2004/Arginase