Item#: RBNP-65A BNP Polyclonal anti-human affinity purified
Product Info:
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| Product Name: | BNP Polyclonal anti-human affinity purified |
|---|---|
| Ab Concentration: | Typically > .1mg/ml |
| Cat. No: | RBNP-65A |
| Form: | Liquid in Phosphate buffered saline pH 7.2 |
| Host: | Rabbit |
| Immunogen: | Human BNP (brain natriuretic peptide-32 ) |
| Storage: | 2-8C |
Polyclonal rabbit anti-human Brain natriuretic peptide BNP Procedure: Rabbits were immunized with brain natriuretic peptide-32 human. Serum was collected and the anti-BNP-32 Brain natriuretic peptide was immunoaffinity purified off an antigen containing immunoabsorbant.
Specification: Optimal working dilutions for anti-brain natriuretic peptide-32 human (BNP-32) should be determined for your particular assay conditions.
Bulk discounts on quantities from 10-100mg of Polyclonal rabbitt anti-human Brain natriuretic peptide BNP
Inquire on our custom polyclonal antibody production. We can host from any species and cross link to your requirements. Custom Polyclonal antibody concentrations available
Human BNP Brain natriuretic peptide research:
Brain natriuretic peptide-BNP 32 (also known as B-type natriuretic peptide or "GC-B") is a 32-amino-acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of myocytes (heart muscles cells) in the ventricles. At the time of release, a co-secreted 76 amino acid n-terminal fragment (NT-proBNP) is also released with B-type natriuretic peptide BNP. B-type natriuretic peptide BNP binds to and activates NPRA in a similar fashion to atrial natriuretic peptide but with 10-fold lower affinity. The biological half-life of BNP however, is twice as long as that of ANP. Both ANP and B-type natriuretic peptide BNP have limited ability to bind and activate NPRB.
BNP 32 Tests showing elevated levels of B-type natriuretic peptide BNP or NT-proBNP in the blood are used as a diagnosis of heart failure and may be useful to establish prognosis in heart failure, as both markers are typically higher in patients with worse outcome.
BNP 32 Both B-type natriuretic peptide BNP and NT-proBNP have been approved as a marker for acute congestive heart failure (CHF). The plasma concentrations of both BNP are increased in patients with asymptomatic and symptomatic left ventricular dysfunction.
BNP 32 Brain natriuretic peptide was originally identified in extracts of porcine brain, but in humans it is produced mainly in the cardiac ventricles.
BNP 32 B-Type Natriuretic Peptide (BNP) blood test: BNP is a substance secreted from the ventricles or lower chambers of the heart in response to changes in pressure that occur when heart failure develops and worsens. The level of B-type natriuretic peptide BNP in the blood increases when heart failure symptoms worsen, and decreases when the heart failure condition is stable. The B-type natriuretic peptide BNP level in a person with heart failure - even someone whose condition is stable - is higher than in a person with normal heart function. REF: Clevelandclinic.org