Item#: 190-29 CK MM Isoenzyme Human
Product Info:
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| Product Name: | CK MM Isoenzyme Human |
|---|---|
| Activity: | Typically >1000 u/ml @ 37C |
| Cat. No: | 190-29 |
| CK Electrophoresis: | 100% CKMM, no CKBB or CKMB detected |
| Expiration: | 1 year |
| Form: | 50% Glycerol,50mM Tris, 2mM DTT at pH 7.5 |
| Purity: | >96% by SDS Page |
| Source: | Human Skeletal Muscle |
| Storage: | 2-8 C |
| UNSPSC code: | 51131907 |
HUMAN CREATINE KINASE MM ISOENZYME CKMM(CK-MM) isoenzyme BULK QUANTITIES from 10-500 mg single lot sizes. As a major bulk manufacturer of cardiac markers we can supply in buffer of your choice.
We are able to supply cardiac markers such as Human CK MB isoenzyme, human troponin I, human troponin T and human troponin C both Native and recombinant. In addition we can provide bulk quantities of C Reactive Protein (CRP) and Myoglobin, for your cardiac requirements
HUMAN CREATINE KINASE CK(CPK) UNIT DEFINITION: One unit will transfer one mmole of phosphate from Creatine Phosphate to ATP per minute at 37C. Measured at 340 nm as one equimolar amount of NADH produced by a coupled reaction.
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190-24 Creatine Kinase MB Isoenzyme from Human heart
191-26R2 r-Creatine Kinase MB Isoenzyme Recombinant Human
190-29 Creatine Kinase MM Isoenzyme from Human muscle
191-27R1 r-Creatine Kinase MM Isoenzyme Recombinant Human
190-10 CREATINE KINASE from Bovine Heart
191-41 CREATINE KINASE from Porcine Heart
191-50 CREATINE KINASE from Rabbit Muscle
191-24 CKBB isoenzyme from Porcine Brain
Human (CK-MM)CKMM isoenzyme also known as human CPK-3 isoenzyme is normally responsible for almost all human (CK)CPK enzyme activity in healthy people. When human (CK-MM)CKMM isoenzyme is elevated, this usually indicates injury or stress to skeletal muscle
Background: Human Creatine phosphokinase (CK)CPK isoenzymes are performed when the total human CPK level is elevated. Human CK(CPK)Isoenzyme testing can help differentiate the source of the damaged tissue. Human (CPK)CK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Human (CKMM)CK-MM, Human (CKBB)CK-BB isoenzyme and Human (CKMB)CK-MB isoenzyme exist.
Human (CKBB)CK-BB isoenzyme occurs mainly in brain and lung tissues. Skeletal muscle expresses Human (CKMM)CK-MM isoenzyme(98%) and human (CKMB)CK-MB isoenzyme at low levels (1%) in muscle. The myocardium (heart muscle), in contrast, expresses human (CKMM)CK-MM isoenzyme at 70% and human (CKMB)CK-MB isoenzyme at 30%.
Predominant human Creatine Kinase Expression
Human CKMM isoenyzme in Skeletal Muscle ,human CKMB isoenzyme in Cardiac Muscle and human CKBB isoenzyme in Brain Tissue and some in lung tissue
Human creatine kinase (CK-MM)CKMM isoenzyme research: Is there an association between ACE and CKMM polymorphisms and cycling performance status during 3-week races. Human creatine kinase (CK-MM)CKMM isoenzymeRef: Int J Sports Med. 2005 Jul-Aug;26(6):442-7/human/isoenzyme/creatine kinase
Human creatine kinase (CK-MM)CKMM isoenzymeresearch:Identification of a CKMM-IgA complex in the serum of a child with Duchenne Muscular Dystrophy. Human creatine kinase (CK-MM)CKMM isoenzyme REF: MA Pesce - ITALIAN JOURNAL OF PEDIATRICS, 2002 - PACINIEDITORE/human/isoenzyme/creatine kinase
Human creatine kinase (CK-MM)CKMM isoenzyme research: Dynamic Changes in Blood IL-6, CK and CK-MM after Skeletal Muscle Damage Induced by Exercise in Rats. Human creatine kinase (CK-MM)CKMM isoenzyme REF: S Quansheng, T Ye, S Junzhi,CHINESE JOURNAL OF SPORTS MEDICINE, 2006 CHINA SPORTS PUBLICATION CORPORATION/human/isoenzyme/creatine kinase
Human creatine kinase (CK-MM)CKMM isoenzyme study: CK-MM Autoantibodies after Skeletal Muscle Injury. Human creatine kinase (CK-MM)CKMM isoenzyme REF:GL Warren, K Rogers, K Billings, LO'Farrell, S,Medicine & Science in Sports & Exercise, 2004 /human/isoenzyme/creatine kinase
Human creatine kinase (CK-MM)CKMM isoenzyme research: CK-MM autoantibodies: prevalence, immune complexes, and effect on CK clearance. Human creatine kinase (CK-MM)CKMM isoenzyme REF: Muscle Nerve. 2006 Sep;34(3):335-46/human/isoenzyme/creatine kinase
Human creatine kinase (CK-MM)CKMM isoenzyme research: Creatine kinase isoenzyme patterns upon chronic exposure to cigarette smoke: Protective effect of Bacoside A.Human creatine kinase (CK-MM)CKMM isoenzyme ref:
Vascular Pharmacology, Volume 42, Issue 2, January 2005, Pages 57-61/human/isoenzyme/ck/mm
Human creatine kinase (CK-MM)CKMM isoenzyme research: Study of the heterogeneity of creatine kinase-MM isoforms using Western blotting.Human creatine kinase (CK-MM)CKMM isoenzyme reference:Clinical Biochemistry, Volume 28, Issue 5, October 1995, Pages 519-525/human/isoenzyme/ck/mm
MM isoenzyme research:Creatine phosphokinase in ectopic pregnancy revisited: Significant diagnostic value of its MB and MM isoenzyme fractions:MM isoenzyme ref:American Journal of Obstetrics and Gynecology, Volume 194, Issue 1,January 2006,Pages 86-91/ck/mm/isoenzyme/human/fractions
Creatine Kinase (CPK)CK research:Comparison of MB Fraction of Creatine Kinase Mass and Troponin I Serum Levels With Necropsy Findings in Acute Myocardial Infarction.Creatine Kinase (CPK)CK ref:The American Journal of Cardiology, 20 December 2007/creatine kinase/cpk/ck/isoenzyme
Creatine Kinase (CPK)CK research:Brain creatine kinase activity in an animal model of mania.Creatine Kinase (CPK)CK ref:Life Sciences, 14 December 2007/creatine kinase/isoenzyme,ck/cpk
Creatine Kinase (CPK)CK study :Changing the substrate specificity of creatine kinase from creatine to glycocyamine: Evidence for a highly evolved active site.Creatine Kinase (CPK)CK source:
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, Volume 1774, Issue 12, December 2007, Pages 1519-1527/cpk/creatine/kinase/ck/isoenzyme
Creatine Kinase (CPK)CK study :Creatine kinase regulation by reversible phosphorylationin a freeze tolerant frog
Creatine Kinase (CPK)CK source :Cryobiology, Volume 55, Issue 3, December 2007, Page 376/cpk/creatine/kinase/ck/isoenzyme
Creatine Kinase (CPK)CK study :Detection of local polarity and conformational changes at the active site of rabbit muscle creatine kinase with a new arginine-specific fluorescent probe.Creatine Kinase (CPK)CK source:Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, online 22 November 2007/cpk/creatine/kinase/ck
Creatine Kinase (CPK)CK research:Is Higher HDL Level Correlated with Smaller Infarct Size Evaluated by Peak CPK?Creatine Kinase (CPK)CK ref:
Journal of Clinical Lipidology, Volume 1, Issue 2, May 2007, Pages 148-149/cpk/creatine/kinase/ck/isoenzyme
Creatine Kinase (CPK)CK research:Significance of CK-elevation in noncompaction with regard to cardiac and neuromuscular disease.Creatine Kinase (CPK)CK ref:
International Journal of Cardiology, In Press,4 December 2007/cpk/creatine/kinase/ck/isoenzyme
Creatine Kinase (CPK)CK research:Mitochondrial biogenesis in fast skeletal muscle of CK deficient mice.Creatine Kinase (CPK)CK source:
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 12 November 2007/cpk/creatine/kinase/ck/isoenzyme
Creatine Kinase (CPK)CK research:An unusual case of congenital muscular dystrophy with normal serum CK level, external ophtalmoplegia, and white matter changes on brain MRI.Creatine Kinase (CPK)CK ref:European Journal of Paediatric Neurology, Volume 11, Issue 6, November 2007, Pages 381-384/cpk/creatine/kinase/ck/isoenzyme
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