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Item #: 190-27
CK Electrophoresis:
100% CKMM, no CKMB or CKBB detected
Protein:
Typically >5 mg protein/ml
Expiration:
1 year
Storage:
2-8 C
Activity:
Typically >1000 u/ml @ 37C
Source:
Human Heart
UNSPSC code:
51131907
Cat. No:
190-27
Form:
50% Glycerol, 50mM Tris, 2mM DTT at pH 7.5
HUMAN CREATINE KINASE MM ISOENZYME CKMM(CK-MM) isoenzyme BULK QUANTITIES from 10-500 mg single lot sizes. As a major bulk manufacturer of cardiac markers we can supply in buffer of your choice.
We are able to supply cardiac markers such as Human CK MB isoenzyme, human troponin I, human troponin T and human troponin C both Native and recombinant. In addition we can provide bulk quantities of C Reactive Protein (CRP) and Myoglobin, for your cardiac requirements
Background: Human Creatine phosphokinase (CK)CPK isoenzymes are performed when the total human CPK level is elevated. Human CK(CPK)Isoenzyme testing can help differentiate the source of the damaged tissue. Human (CPK)CK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Human (CKMM)CK-MM, Human (CKBB)CK-BB isoenzyme and Human (CKMB)CK-MB isoenzyme exist.
Human (CKBB)CK-BB isoenzyme occurs mainly in brain and lung tissues. Skeletal muscle expresses Human (CKMM)CK-MM isoenzyme(98%) and human (CKMB)CK-MB isoenzyme at low levels (1%) in muscle. The myocardium (heart muscle), in contrast, expresses human (CKMM)CK-MM isoenzyme at 70% and human (CKMB)CK-MB isoenzyme at 30%.