COENZYME Nicotinamide-Adenine Dinucleotide Phosphate (NADPH), Reduced Form Tetrasodium Salt

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Item #: 94330

Details

beta Nicotinamide-Adenine Dinucleotide Phosphate, Reduced (beta-NADPH) tetrasodium salt available in kgs quantities

Nicotinamide adenine dinucleotide phosphate (NADP+, in older notation triphosphopyridine nucleotide, TPN) is used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.

NADPH is the reduced form of NADP+, and NADP+ is the oxidized form of NADPH. NADP+ differs from NAD+ by the presence in NADP+ of an additional phosphate group on the 2' position of the ribose ring that carries the adenine moiety.The oxidative phase of the pentose phosphate pathway is the major source of NADPH in cells, producing approximately 60% of the NADPH required.
UV Spectral Analysis: Ratios at pH 10.0
A340/A260 (0.43 + or - 0.02)
Extinction Coeffientat 260nm(14.4 + or - 0.5) x 10000
Extinction Coeffient at 340nm (6.2 + or - 0.2) x 10000

Unstable in acids, but relatively stable at pH 10-1

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