COENZYME BETA Nicotinamide-Adenine Dinucleotide (NAD+), Oxidized Form Free Acid

• High Purity Proteins
• Recombinant Proteins
• Antibodies
• Biologicals
• Fine Biochemicals
• Reagents

Item #: 94050

Details

beta NAD Nicotinamide-Adenine Dinucleotide, Oxidized Form available in kgs quantities

Nicotinamide adenine dinucleotide, abbreviated NAD+, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups: with one nucleotide containing an adenine base, and the other containing nicotinamide.
UV Spectral Analysis:
Ratios at pH 7.5
A250/A260 (0.83 ± 0.03)
A280/A260 (0.21 + or - 0.02)
å at 260 nm (18.0 + or - 0.5) x 103
Ratios at pH 10 after reduction with ADH*
A340/A260 (0.43 + or - 0.01)
å at 340 nm (6.3 + or - 0.2) x 10000

The enzymes that make and use NAD+ and NADH are important in both current pharmacology and the research into future treatments for disease.Drug design and drug development exploits NAD+ in three ways: as a direct target of drugs, by designing enzyme inhibitors or activators based on its structure that change the activity of NAD-dependent enzymes, and by trying to inhibit NAD+ biosynthesis.

The coenzyme NAD+ is not itself currently used as a treatment for any disease. However, it is potentially useful in the therapy of neurodegenerative diseases such as Alzheimer's and Parkinson disease.

Popular Products