Item#: 535-11 TRANSFERRIN HOLO Human
Product Info:
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| Product Name: | TRANSFERRIN HOLO Human |
|---|---|
| CAS No: | 11096-37-0 |
| Cat. No: | 535-11 |
| Expiration: | 2 years |
| Form: | Lyophilized |
| Molecular Weight: | 77 000 |
| Purity: | >96% by SDS Polyacrylamide Gel |
| Reconstitution: | Dionized water |
| Source: | Human Serum |
| Storage: | 2-8 C |
| Synonyms: | Transferrin iron-saturated, Siderophilin,TRF |
| UNSPSC code: | 51131907 |
HUMAN HOLO TRANSFERRIN ,Transferrin iron-saturated, (Siderophilin,TRF,TF) BULK QUANTITIES from 50-5000gram single lot sizes. Custom fills of human holo transferrin available. Human Holo transferrin custom buffers available on bulk orders.
Purification procedures include selective size exclusion, ion exchange chromatography and gel fitration for transferrin products.
Ultra Pure Human Holo Transferrin >99% pure available upon request.
Transferrin products we offer:
535-12 Human APO TRANSFERRIN from Human Serum
535-50 Rat APO TRANSFERRIN from Rat Serum
535-11 Human HOLO TRANSFERRIN (TF) from Human Serum
CTX-80A Transferrin, Polyclonal Chicken anti-Human Affinity Purified antibody
Human holo Transferrin(Transferrin iron-saturated, Siderophilin,tf,TRF) SDS-Polyacrylamide gel electrophoresis shows one major band only corresponding to the molecular weight of human Transferrin.
Human Transferrin is a plasma protein for iron ion delivery. Human Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron binding domains. Transferrin(TF) is related to other iron binding proteins including lactoferrin. When human transferrin loaded with iron encounters a transferrin receptor on the surface of a cell, it binds to it and is consequently transported into the cell in a vesicle. The cell will acidify the vesicle, causing human transferrin(TF) to release its iron ions. Each human transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+).
Human Transferrin levels may be checked in iron deficiency, hemochromatosis and other iron overload disorders. Transferrin is also associated with the innate immune system. Human Transferrin is found in the mucosa and binds iron, thus creating an environment low in free iron, where few bacteria are able to survive.
Human Transferrin is offered as a lyophilized powder in both human Apo transferrin (iron-free) and human Holo transferrin(iron-saturated) forms.
Human Holo transferrin, holotransferrin study: Intact human holo-transferrin interaction with oxaliplatin. Human holo Transferrin REF: Rapid Communications in Mass Spectrometry Volume 19,Issue 14,Pages 1956-1962/holo/human/Transferrin.
Human Holo transferrin, holo transferrin article: The Cytoplasmic Domain of Transferrin Receptor 2 Dictates Its Stability and Response to human Holo-transferrin in Hep3B Cells. Human holo Transferrin REF: J. Biol. Chem., Vol. 282, Issue 9, 6201-6209, March 2, 2007/holo/human/Transferrin.
Human transferrin research: Serum Transferrin Receptor Concentrations during Normal Pregnancy. Human Transferrin REF: Clinical Chemistry 46: 725-727, 2000/holo/human/Transferrin.
Human Holo transferrin, holotransferrin study: Circulating Soluble Transferrin Receptor According to Glucose Tolerance Status and Insulin Sensitivity. Human Transferrin REF: Diabetes Care 30:604-608, 2007/holo/human/Transferrin.
Human Holo transferrin and apo transferrin study: A structural comparison of human serum transferrin and human lactoferrin. Human holo Transferrin REF:Biometals. 2007 Jan 11/holo/human/Transferrin.
Human holo transferrin and apo transferrin study: Quercetin-induced Conformational Change of Human Serum Transferrin. Human Transferrin REF: Chemistry Letters Vol. 36 (2007) , No. 1 p.84 /holo/human//Transferrin.
Human Holo transferrin, holotransferrin study: Decreased transferrin receptor expression by neuromelanin cells in restless legs syndrome. Human holo Transferrin REf: NEUROLOGY 2004;62:1563-1567/holo/human/Transferrin.
Human Holo transferrin, research: Effects of artemisinin-tagged holotransferrin on cancer cells. Human holo transferrin REF:Life Sciences, Volume 76, Issue 11, 28 January 2005, Pages 1267-1279/holo/human/Transferrin.
Human holo transferrin article: The growth inhibition exhibited by the feoB mutant in Fe-deficient media was relieved by human holo-transferrin, human holo-lactoferrin and Fe3+-dicitrate, but not by FeSO4. Human holo Transferrin REF:Molecular Microbiology Volume 37 Issue 2 Page 274,July 2000 /holo/human//Transferrin.
Human holo transferrin research: Iron absorption and cellular transport. This study postulates that the basolateral membranes of absorptive cells possess both human holo-transferrin and human apotransferrin receptors that regulate the ingress and egress of cellular iron. Human holo Transferrin REF: Semin Hematol. 1998 Jan;35(1):13-26/holo/human/Transferrin.
Human Holo Transferrin research: Human Apo transferrin and Human holotransferrin(holo transferrin) undergo different endocytic cycles in intestinal epithelia (Caco-2) cells. Human holo Transferrin REF:J Biol Chem. 1997 Aug 1;272(31):19425-8/holo/human/Transferrin.
Human Holo transferrin articles are for information purposes only. Lee Biosolutions human holo transferrin is for research and further manufacturing use only.
Human transferrin Research: The C2 variant of human serum transferrin retains the iron binding properties of the native protein. Human transferrin REF: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Volume 1741, Issue 3, 25 September 2005, Pages 264-270/holo/human/Transferrin.
Human holo transferrin research: Relationship Between Transferrin-Iron Saturation, Alcohol Consumption, and the Incidence of Cirrhosis and Liver Cancer. Human holo transferrin REF:
Clinical Gastroenterology and Hepatology, Volume 5, Issue 5, May 2007, Pages 624-629/holo/human/Transferrin.
Human holo tranferrin research: Aluminum stimulates uptake of non-transferrin bound iron and transferrin bound iron in human glial cells. Human holo transferrin REF: Toxicology and Applied Pharmacology, Volume 220, Issue 3, 1 May 2007, Pages 349-356/holo/Transferrin/human.
Transferrin is a blood plasma protein for iron ion delivery.
en.wikipedia.org/wiki/Transferrin
TIBC and transferrin tests are ordered, how they are used, and what the results of a TIBC or transferrin test might mean.www.labtestsonline.org/understanding/analytes/tibc/test.html
Essentially all circulating plasma iron normally is bound to transferrin. sickle.bwh.harvard.edu/iron_transport.html
Human holo Transferrin Research:
Huma Holo-Transferrin and Thrombin Can Interact to Cause Brain Damage. Human holo Transferrin REF: Stroke. 2005;36:348/holo/Transferrin/human.
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