Item#: 535-12 TRANSFERRIN APO Human
Product Info:
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| Product Name: | TRANSFERRIN APO Human |
|---|---|
| Appearance: | Light Pink Powder |
| CAS No: | 11096-37-0 |
| Cat. No: | 535-12 |
| Expiration: | 2 years |
| Form: | Lyophilized in ammonia bicarbonate buffer. pH 7.2 |
| Iron Assay: | less than .02 mg/g of protein |
| Molecular Weight: | 77kD |
| Purity: | >99% by SDS-Polyacrylamide Gel |
| Reconstitution: | Deionized Water |
| Source: | Human Serum |
| Storage: | 2-8 C |
| Synonyms: | Siderophilin, TRF,apo-hTF , apotransferrin |
| UNSPSC code: | 51131907 |
HUMAN APO TRANSFERRIN HIGH PURITY BULK QUANTITIES from 50-5000gram single lot sizes. Human Apo Transferrin custom fills available. Human Apo transferrin custom buffers available.
Purification procedures include selective size exclusion, ion exchange chromatography and gel fitration for transferrin products.
Transferrin products we offer:
535-12 Human APO TRANSFERRIN from Human Serum
535-50 Rat APO TRANSFERRIN from Rat Serum
535-11 Human HOLO TRANSFERRIN (TF) from Human Serum
CTX-80A Transferrin, Polyclonal Chicken anti-Human Affinity Purified antibody
Human Transferrin is offered as a lyophilized powder in both Apo (iron-free) and Holo (iron-saturated) forms
Human APO Tranferrin is iron saturated. Each Human transferrin molecule binds with two Fe3+ ions to form a reddish complex
Human Transferrin is a serum protein involved in iron binding and transport. APO Human Transferrin is Substantially iron-free.
Human apo Transferrin ANALYSIS: Total protein determination by the Lowry method. SDS-Polyacrylamide gel electrophoresis shows one major band only corresponding to the molecular weight of Transferrin.
Human Transferrin is a plasma protein for iron ion delivery. Human Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron binding domains. Human Transferrin is related to other iron binding proteins including lactoferrin. When human transferrin loaded with iron encounters a human transferrin receptor on the surface of a cell, it binds to it and is consequently transported into the cell in a vesicle. The cell will acidify the vesicle, causing human transferrin to release its iron ions. Each human transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+).
Human Transferrin levels may be checked in iron deficiency, hemochromatosis and other iron overload disorders. Transferrin is also associated with the innate immune system. Human Transferrin is found in the mucosa and binds iron, thus creating an environment low in free iron, where few bacteria are able to survive.
Human Apo transferrin Research: Single particle reconstruction of the human apo-transferrin–transferrin receptor complex. Human apo transferrin REF:
Journal of Structural Biology, Volume 152, Issue 3, December 2005, Pages 204-210/apo/Transferrin/human.
Human Apo transferrin research: The Crystal Structure of Iron-free(apo transferrin) Human Serum Transferrin Provides Insight into Inter-lobe Communication and Receptor Binding. Human APO Transferrin REF: J. Biol. Chem., Vol. 281, Issue 34, 24934-24944, August 25, 2006/apo/Transferrin/human.
Human Apo transferrin study: The Cleavage of Pyrophosphate by Human Serum apo-transferrin. Human Transferrin REF: WQ Zhong, WB Tang, Y Zhang/apo/Transferrin/human.
Human apo transferrin,apotransferrin research: The Effect of Apo-Transferrin on Bacterial Adhesion to Biomaterials. Human Human Apo transferrin REF: Artificial Organs
Volume 26 Issue 6 Page 512 - June 2002/apo/Transferrin/human.
Human apo transferrin,apotransferrin research.:Serum Transferrin Receptor Concentrations during Normal Pregnancy. Human Human Apo transferrin REF: Clinical Chemistry 46: 725-727, 2000/apo/Transferrin/human.
Human apo transferrin,apotransferrin research: Circulating Soluble Transferrin Receptor According to Glucose Tolerance Status and Insulin Sensitivity. Human Human Apo transferrin REF: Diabetes Care 30:604-608, 2007/apo/Transferrin/human.
Transferrin is a blood plasma protein for iron ion delivery.
en.wikipedia.org/wiki/Transferrin
TIBC and transferrin tests are ordered, how they are used, and what the results of a TIBC or transferrin test might mean.www.labtestsonline.org/understanding/analytes/tibc/test.html
Essentially all circulating plasma iron normally is bound to transferrin. sickle.bwh.harvard.edu/iron_transport.html
Human apo transferrin,apotransferrin research: A structural comparison of human serum transferrin and human lactoferrin. Human Apo transferrin REF:Biometals. 2007 Jan 11/apo/Transferrin/human.
Human apo transferrin,apotransferrin research: Quercetin-induced Conformational Change of Human Serum Transferrin. Human Human Apo transferrin REF: Chemistry Letters Vol. 36 (2007) , No. 1 p.84/apo/Transferrin/human.
Human apo transferrin,apotransferrin study: Decreased transferrin receptor expression by neuromelanin cells in restless legs syndrome.Human Apo transferrin REf: NEUROLOGY 2004;62:1563-1567/apo/Transferrin/human.
Human holo transferrin and Human apo transferrin,apotransferrin research: Iron absorption and cellular transport. This study postulates that the basolateral membranes of absorptive cells possess both human holo-transferrin and human apotransferrin receptors that regulate the ingress and egress of cellular iron. Human Apo and holo transferrin REF: Semin Hematol. 1998 Jan;35(1):13-26/apo/Transferrin/human.
Human apo transferrin,apotransferrin study: Human Apo transferrin and Human holotransferrin(holo transferrin) undergo different endocytic cycles in intestinal epithelia (Caco-2) cells. Human Apo transferrin REF:J Biol Chem. 1997 Aug 1;272(31):19425-8/apo/Transferrin/human.
Human apo transferrin,apotransferrin research: Thermodynamic domain analysis of fresh and incubated human apotransferrin.Human apo transferrin,apotransferrin REF:
Thermochimica Acta, Volume 383, Issues 1-2, 7 February 2002, Pages 103-108/apo/Transferrin/human.
Human APO Transferrin Research:
Apo-transferrin is internalized and routed differently from Fe-transferrin by Caco-2 cells: a confocal microscopy study of vesicular transport in intestinal cells. Human APO Transferrin REF: Blood, Vol. 95 No. 2 (January 15), 2000: pp. 721-723/apo/Transferrin/human.
Human Apo and holo transferrin articles are for information purposes only. Lee Biosolutions human apo transferrin is for research and further invitro manufacturing use only. Lee Biosolutions human apo transferrin is not for human therapeutic use.
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