Item#: 350-50R LACTATE DEHYDROGENASE, (Recombinant)

Unit Definition: One unit is defined as 1umol of NAD+ production per minute at 25C, pH 7.0. From cloned LDH-B gene from chicken heart cDNA library. pH stability from 6.0-10.0.

Inquire on Bulk quantities of 1-10 million unit single lot sizes.

We manufacture all the Human Lactate Dehydrogenase LD(LDH) isoenzyme(s):
350-75 Total Human Lactate Dehydrogenase LDH
355-12 Total Human Lactate Dehydrogenase LDH
355-15 Lactate dehydrogenase LD1, LDH-1 ISOENZYME(s) Human Heart
355-10 Lactate Dehydrogenase LD1, LDH-1 ISOENZYME(s) Human Erythrocytes
355-16 Lactate Dehydrogenase LD1, LDH-1 ISOENZYME(s) Human Heart
355-20 Lactate Dehydrogenase LD2, LDH-2 ISOENZYME(s) Human Erythrocytes
355-25 Lactate dehydrogenase LD2, LDH-2 ISOENZYME(s) Human Heart
355-30 Lactate Dehydrogenase LD3, LDH-3 ISOENZYME(s) Human Erythrocytes
355-35 Lactate Dehydrogenase LD3, LDH-3 ISOENZYME Human Heart
355-40 Lactate Dehydrogenase LD4, LDH-4 ISOENZYME Human Liver
355-50 Lactate Dehydrogenase LD5, LDH-5 ISOENZYME Human Liver

Lactate dehydrogenase (LDH) is an enzyme (EC 1.1.1.27) present in a wide variety of organisms, including plants and animals. Lactate Dehydrogenase (LDH) catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. Lactate Dehydrogenase(LDH) can also catalyze the oxidation of hydroxybutyrate, it is occasionally called Hydroxybutyrate Dehydrogenase (HBD).

Meningitis and encephalitis
The enzyme is also found in cerebrospinal fluid where high levels of lactate dehydrogenase in cerebrospinal fluid are often associated with bacterial meningitis. High levels of the enzyme can also be found in cases of viral meningitis, generally indicating the presence of encephalitis and poor prognosis.
HIV and elevated LDH.

LDH is often measured in HIV patients as a non-specific marker for Pneumocystis jiroveci (formerly Pneumocystis carinii) pneumonia (PCP). Elevated LDH in the setting of upper respiratory symptoms in an HIV patient suggests, but is not diagnostic for, PCP.