Lee Biosolutions Inc, a U.S. manufacture of high purity finished proteins has increased production capacity for important enzymes used in liver function blood tests worldwide. The St. Louis-based healthcare- biotechnology firm has been able to keep up with demand for aminotransferase enzymes by increasing yields through newly developed purification methodologies.
The liver is not only the largest organ but the largest gland in the human body which plays an important role by filtering and processing blood as it circulates through the body. The functions of the liver include detoxification of your blood, production of important clotting factors and other proteins, processing nutrients, waste products of hemoglobin and storing vitamins, cholesterol and bile while also producing glucose. The cells in the liver contain proteins called enzymes that drive these chemical reactions. When the liver cells are damaged or destroyed, the enzymes in the cells leak out to the blood where they can be measured by blood tests. The liver function tests include measuring two main enzymes, Aspartate Aminotransferase called AST (GOT) and Alanine Aminotransferase ALT (SGPT) which when elevated is a strong sign of liver damage or disease.
According to Burton Lee, President of Lee Biosolutions, “The enzymes that are produced for liver function tests are actually isolated from porcine and bovine sources at our facility in St. Louis. Our production chemists process literally thousands of kgs of high quality tissue from USDA slaughter houses at a time in order to isolate and purify just a few hundred grams of a single enzyme. Careful monitoring of critical points in the process is needed to insure a stable high quality product. Our finished enzymes are then purchased under strict specifications by major IVD companies such as Bio-Rad Laboratories who produce the reagents and blood tests for hospitals to aid in the diagnoses if someone has alcoholic liver disease, viral hepatitis, and acute or chronic liver injury. Its very satisfying to know the products that you produce are helping save lives.”
About Lee Biosolutions, Inc.
Lee Biosolutions is an international producer high purity finished proteins. Headquartered in St. Louis and founded in 2002, the healthcare biotechnology firm serves academic and scientific researchers as well as IVD manufacturers worldwide. Lee BioSolutions produces and processes proteins and antibodies used in drug discovery and development, clinical diagnostic and immunodiagnostic market. The company is ISO 9001:2008 certified, has an active fan base on facebook ,is FDA and APHIS certified. To learn more about Lee BioSolutions visit http://www.LeeBio.com.