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Item #: 426-10
> 0.8 (A280/A430)
> 96% (SDS-PAGE)
1.0 - 2.0 mg/mL (A280 E=1.45)
50mM sodium acetate, pH 6.0, with NaCl
Clear, greenish Liquid
Typically > 500 U/mL
Unit Definition: One unit of Myeloperoxidase will catalyze the consumption of one micromole of hydrogen peroxide and the production of 1/4 micromole of tetraguaiacol per minute at pH 7.0 and 25C.
Lee Biosolutions is the largest producer and supplier of Myeloperoxidase enzymes, P-ANCA autoimmune antigen, for research, life science and diagnostic manufacturing.
Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Related Products Offered:
186-10 Human Neutrophil Cathepsin G
497-50 Human Neutrophil Proteinase 3 (PR3)
426-10A - Human Myeloperoxidase - Isoform A
426-10B - Human Myeloperoxidase - Isoform B
426-10C - Human Myeloperoxidase - Isoform C
Rz is an abbreviation for Reinheitszahl (purity number). It is the ratio of absorbance at 430 nm (heme)/ 280 nm (total protein). It is a measure of the purity of the enzyme. Anything above 0.8 is highly pure.
MPO is a peroxidase enzyme occurs the most in neutrophil granulocytes (a subtype of white blood cells). It is a lysosomal protein stored in azurophilic granules of the neutrophil. Myeloperoxidase has a green heme pigment and is found in pus and some forms of mucus. It is recognized as an important factor in many inflammatory diseases such as cardiovascular and neurological diseases. MPO-specific imaging agents would thus be highly useful to diagnose early disease, monitor disease progression, and quantify treatment effects.