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Item #: 342-40
Neutrophil Elastase - Grade II
Typically >50 u/mL @ 37C
>25 units/mg protein
>96% by SDS-PAGE
ELA-2, Elastase, hne
0.05 M sodium acetate, 0.6 M sodium chloride, pH 5.5
Typically >1.0 mg/mL
IN STOCK - Ships same day
Lee Biosolutions is the leading producer of HUMAN ELASTASE from HUMAN Neutrophils, for clinical research and diagnostic manufacturing.
Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Human Neutrophils, also known as neutrophilic polymorphonuclear leukocytes, are the major class of white blood cell in human peripheral blood. They, have a multilobed nucleus and neutrophilic granules, and are phagocytes and have an important role in engulfing and killing extracellular pathogens.
The neutrophil form of elastase is 218 amino acids long, with two asparagine-linked carbohydrate chains. Current studies show that both Cathepsin G and Neutrophil Elastase are key enzymes for tissue injury caused by activated neutrophils, such as occurs in Acute Lung injury.
One unit will hydrolyze one micromole of methoxy succinyl-alanine-alanine-proline-valine-p-nitroanilide per minute at 37C and pH 7.5