Item#: 129-15 NT- ProBNP ( recombinant )
Product Info:
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| Product Name: | NT- ProBNP ( recombinant ) |
|---|---|
| Cat. No: | 129-15 |
| Form: | Lyophilized from 200mM ammonium acetate buffer |
| Purity: | > 80% by SDS Page |
| Source: | Expressed in E. Coli |
| Storage: | -20C |
N-terminal pro-B-type natriuretic peptide NT-proBNP: Tests showing elevated levels of BNP or NT-proBNP in the blood are used as a diagnosis of heart failure and may be useful to establish prognosis in heart failure, as both markers are typically higher in patients with worse outcome.
Both BNP and N-terminal pro-B-type natriuretic peptide NT-proBNP have been approved as a marker for acute congestive heart failure (CHF). The plasma concentrations of both BNP are increased in patients with asymptomatic and symptomatic left ventricular dysfunction.
N-terminal pro-B-type natriuretic peptide NT-ProBNP: Many studies have demonstrated the clinical utility of measuring plasma concentrations of NP(s), including NT-proBNP. NP(s) have been suggested as the biomarkers of choice for diagnosis and risk stratification of patients with heart failure NT ProBNP REF: (Boomsma et al. Cardiovascular Research 51:442-449 2001/nt/probnp/bnp
NPs have been shown to have good prognostic value with regards to both morbidity and mortality in heart failure. Several studies have also demonstrated the utility of NP measurements in the prediction of left ventricular dysfunction and survival following acute myocardial infarction NT ProBNP REF:Richards et al. Circulation 97:1921-1929 1998/nt/probnp/bnp
N-terminal pro-B-type natriuretic peptide NT ProBNP research: Multiple Biomarker Use for Detection of Adverse Events in Patients Presenting with Symptoms Suggestive of Acute Coronary Syndrome. measured 7 biomarkers: myeloperoxidase (MPO), soluble CD40 ligand (CD40L), placental growth factor (PlGF), metalloproteinase-9 (MMP-9), high-sensitivity C-reactive protein (hsCRP), cardiac troponin I (cTnI), and N-terminal pro-B-type natriuretic peptide (NT-proBNP).NT ProBNP REF: Clinical Chemistry. 2007;53:874-881/nt/probnp/bnp/pro
NT ProBNP research:Serial NT-proBNP monitoring and outcomes in outpatients with decompensation of heart failure .NT ProBNP ref:
International Journal of Cardiology, Volume 120, Issue 3, 3 September 2007, Pages 338-343/nt/probnp/bnp/pro
NT ProBNP research:NT-proBNP, IGF-I and survival in patients with chronic heart failure.NT ProBNP resf:Growth Hormone & IGF Research, Volume 17, Issue 4, August 2007, Pages 288-296/nt/probnp/bnp/pro
NT ProBNP research:Increased Ratio of NT-proBNP to BNP might be Associated with Cardiac Mortality in Patients Hospitalized for Worsening CHF.NT ProBNP ref:Journal of Cardiac Failure, Volume 13, Issue 6, Supplement 1, August 2007, Pages S30-S31/nt/probnp/bnp/pro
NT ProBNP research:Exercise training in advanced heart failure patients: Discordance between improved exercise toleranceand unchanged NT-proBNP levels.NT ProBNP research:
International Journal of Cardiology, 24 July 2007,/nt/probnp/bnp/pro
NT ProBNP research:Association between anaemia and N-terminal pro-B-type natriuretic peptide (NT-proBNP): Findings from the Heart and Soul Study.NT ProBNP research:
European Journal of Heart Failure, In Press, Corrected Proof, Available online 12 July 2007/nt/probnp/bnp/pro
NT ProBNP research:Persistent NT-proBNP elevation in acute pulmonary embolism predicts early death.NT ProBNP ref:
Clinica Chimica Acta, Volume 382, Issues 1-2, July 2007, Pages 124-128/nt/probnp/bnp/pro