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Pepsinogen I (PGI/PGA), Human Stomach

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Item #: 440-01

Description

Purity:

>90% (SDS-PAGE, confirmed via Western Blot)

Molecular Weight:

45 kDa

Synonyms:

Pepsinogen A, PG1, PGA

Availability:

REPLACED WITH 440-50

Source:

Human Gastric Mucosa, Human Stomach

Product Name:

Pepsinogen I

Protein:

>0.5 mg/mL

Recertification:

1 year

Catalogue Number:

440-01

UNSPSC code:

51131907

Storage:

2-8 C

Form:

Liquid

Price

Unit

Qty

Details

Lee Biosolutions is the leading producer and supplier of human gastric Pepsinogen I (A) antigen as a cancer marker for medical research, clinical and biomedical manufacturing.

Technical support, bulk quantities and aliquoting available, email info@leebio.com for more details.

Other Pepsinogen products available:
440-01 - Human Pepsinogen I (PGI/PGA)
440-02 - Human Pepsinogen II (PGII/PGC)
991-92 - Human Stomach Tissue


Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II).

Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis.

It has been reported that human Pepsinogen I (PGA)levels were lower in atrophic corpus gastritis than in atrophic antral gastritis, and human pepsinogen I(PGA) levels were lower in advanced gastric cancer than early stage gastric cancer

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