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Item #: 440-01
>90% (SDS-PAGE, confirmed via Western Blot)
Pepsinogen A, PG1, PGA
REPLACED WITH 440-50
Human Gastric Mucosa, Human Stomach
Lee Biosolutions is the leading producer and supplier of human gastric Pepsinogen I (A) antigen as a cancer marker for medical research, clinical and biomedical manufacturing.
Technical support, bulk quantities and aliquoting available, email email@example.com for more details.
Other Pepsinogen products available:
440-01 - Human Pepsinogen I (PGI/PGA)
440-02 - Human Pepsinogen II (PGII/PGC)
991-92 - Human Stomach Tissue
Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II).
Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis.
It has been reported that human Pepsinogen I (PGA)levels were lower in atrophic corpus gastritis than in atrophic antral gastritis, and human pepsinogen I(PGA) levels were lower in advanced gastric cancer than early stage gastric cancer