Item#: CB2-80A beta 2-Microglobulin, Polyclonal anti-Human Affinity Purified (B2M)
Product Info:
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| Product Name: | beta 2-Microglobulin, Polyclonal anti-Human Affinity Purified (B2M) |
|---|---|
| Ab Concentration: | Typically > 1mg/ml |
| Cat. No: | CB2-80A |
| Form: | Liquid in PBS, pH 7.2 |
| Host: | Chicken |
| Immunogen: | Human (B2M) Beta 2 Microglobulin |
| Purity: | Affinity Purified |
| Storage: | 2-8C |
Beta 2-microglobulin Polyclonal Antibody Procedure: Chickens were immunized with highly purified human beta 2-microglobulin isolated from human urine. The resulting anti-human beta 2-microglobulin was solid phase absorbed then affinity purified off an antigen containing immunoabsorbant.
Polyclonal antibody Specification: This anti-human beta 2-microglobulin is suitable for depletion, ELISA and Botting applications.
Western Blots 1:1,000
ELISA coating 1:200-1:500
Inquire on bulk quantities of polyclonal anti human Beta 2 microglobulin from 50-500mg single lot sizes
Inquire on our custom polyclonal antibody production. We can host from any species and cross link to your requirements. Custom Polyclonal antibody concentrations available
Human Beta 2-Microglobulin protein(B2M) Products we offer:
126-11R (B2M)Beta 2 Microglobulin Human Recombinant
126-11 Native Human Beta Microglobulin (B2M)
CB2-80A Polyclonal chicken anti-human beta 2-Microglobulin (anti-B2M)
Human Beta 2 Microglobulin (human B2M)
Human beta 2 microglobulin (B2M)is a component of MHC class I molecules, which are present on almost all cells of the body (red blood cells are a notable exception). Human beta 2 microglobulin (B2M) lies lateral to the alpha3 chain on the cell surface. Unlike alpha3, human beta 2 microglobulin (B2M) has no transmembrane region. Directly above human beta 2 microglobulin (B2M) (i.e. away from the cell) lies the α1 chain, which itself is lateral to the alpha2. human beta 2 microglobulin (B2M) microglobulin associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa.
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Human beta 2 microglobulin (B2M)is a component of MHC class I molecules, which are present on almost all cells of the body (red blood cells are a notable exception). Human beta 2 microglobulin (B2M) lies lateral to the alpha3 chain on the cell surface. Unlike alpha3, human beta 2 microglobulin (B2M) has no transmembrane region. Directly above human beta 2 microglobulin (B2M) (i.e. away from the cell) lies the α1 chain, which itself is lateral to the alpha2. human beta 2 microglobulin (B2M) microglobulin associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa.
Human Beta 2 microglobulin, B2 Microglobulin research: Beta-2 Microglobulin and Soluble Interleukin-2 Receptor Serum Levels Correlates with Human Immunodeficiency Virus Associated Non-Hodgkins Lymphoma-Diffuse Large B-Cell Lymphoma (HIV-NHL-DLBCL. Human Beta 2-microglobulin (B2M) REF: Blood (ASH Annual Meeting Abstracts) 2005 106: Abstract 4675/human/b2m/beta 2 microglobulin/polyclonal/antibody
Human Beta 2-microglobulin (B2M)research: A simple method to predict protein-binding from aligned sequences—application to MHC superfamily and B2-microglobulin(human beta 2 microglobulin). (Human Beta 2-microglobulin (B2M) REF:Bioinformatics 2006 22(4):453-459/human/b2m/beta 2 microglobulin/polyclonal/antibody
human beta 2 microglobulin (B2M)significance: In patients on long-term hemodialysis, human beta 2 microglobulin (B2M) can aggregate into amyloid fibers that deposit in joint spaces, a disease known as dialysis-related amyloidosis
Human Beta 2-microglobulin (B2M) research: Human beta 2 Microglobulin (b2 microglobulin)Is an Androgen-Regulated Secreted Protein Elevated in Serum of Patients with Advanced Prostate Cancer. Human Beta 2-microglobulin (B2M)REF: Clinical Cancer Research 13, 1979-1986, April 1, 2007/human/b2m/beta 2 microglobulin/polyclonal/antibody
Human Beta 2-microglobulin (B2M) research: Properties of Some Variants of Human beta 2-Microglobulin and Amyloidogenesis. Human Beta 2-microglobulin (B2M)REF: J. Biol. Chem., Vol. 279, Issue 10, 9176-9189, March 5, 2004/human/b2m/beta 2 microglobulin/polyclonal/antibody
Human Beta 2-microglobulin (B2M)study: Human B2-Microglobulin(beta 2 microglobulin) Is a Signaling and Growth-Promoting Factor for Human Prostate Cancer Bone Metastasis. Human Beta 2-microglobulin (B2M)REF:Cancer Research 66, 9108-9116, September 15, 2006 /human/b2m/beta 2 microglobulin/polyclonal/antibody
Human B2M-Human Beta 2 Microglobulin Research: Human Beta 2-microglobulin protein (B2M) is a low molecular-weight protein synthesized by all nucleated cells. Human Beta 2-microglobulin protein (B2M) is a clinically useful marker for following treatment response of patients with malignant lymphoma or multiple myeloma. Human Beta 2-microglobulin (B2M) Serum concentrations are related to tumor burden. Human Beta 2-microglobulin (B2M) is also elevated in benign diseases; including rheumatoid arthritis, systemic lupus erythematosus, sarcoidosis and some viral diseases.
Human Beta 2-microglobulin protein (B2M) has been found in the human serum of normal individuals and in the urine in elevated amounts in patients with Wilson disease, cadmium poisoning, and other conditions leading to renal tubular dysfunction
Human Beta 2-microglobulin (human B2M): Human Beta 2-microglobulin protein(B2M)Research shows that Human Beta 2 Microglobulin (B2M) plays an important role in regulating the elimination of tumor cells, which occurs as a result of the action of Human Beta 2-microglobulin (B2M) protein as an apoptosis-inducing factor. Human Beta 2-microglobulin (B2M) Ref: Blood,Vol.94 No.8 (October 15),1999:pp.2744-2753/human/b2m/beta 2 microglobulin/polyclonal/antibody
Human Beta 2-microglobulin (human B2M) study suggest that there is post-transcriptional regulation of Human Beta 2-microglobulin (B2M) generation and/or release as well as the influence of the dialyzer membrane type on post-translational processes, that is, advance glycation end products (AGE) or conformational modification of the Human Beta 2-microglobulin (B2M) protein.(B2M)REF: Kidney International (2001) 59, S177–S181/human/b2m/beta 2 microglobulin/polyclonal/antibody
Beta 2 Microglobulin study:Targeting beta2-Microglobulin Mediated Signaling as a Novel Therapeutic Approach for Human Renal Cell Carcinoma.Beta 2 Microglobulin ref:The Journal of Urology, Volume 178, Issue 1, July 2007, Pages 292-300/beta/2/microglobulin
Beta 2 Microglobulin study:Beta-2-microglobulin-deficient mice: increased susceptibility to Mycobacterium avium infection.Beta 2 Microglobulin ref:
International Journal of Antimicrobial Agents, Volume 29, Supplement 2, March 2007, Page S494/beta/2/microglobulin
Beta 2 Microglobulin study:Clinical relevance of soluble HLA-I and b2m β2-microglobulin levels in non-Hodgkin's lymphoma and Hodgkin's disease.Beta 2 Microglobulin ref:Leukemia Research, Volume 31, Issue 2, February 2007, Pages 139-145/human/beta/2/microglobulin
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