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Human Serum TRANSFERRIN APO, Iron Free

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Item #: 535-12

Description

Synonyms:

Siderophilin, TRF,apo-hTF , apotransferrin

Expiration:

2 years

Appearance:

Light Pink Powder

Product Name:

APO Transferrin

Source:

Human Serum

Storage:

2-8 C

Molecular Weight:

77kDa

Purity:

>99% by SDS-PAGE

UNSPSC code:

51131909

CAS Number:

11096-37-0

Iron Assay:

< 30 ppm

Catalogue Number:

535-12

Availability:

IN STOCK - Ships same day

Form:

Lyophilized in Ammonium Bicarbonate buffer, pH 7.2

Endotoxin Level:

< 1 EU/mg

Price

Unit

Qty

$375.00

1g

$195.00

500mg

$115.00

100mg

$65.00

50mg

Details

Lee Biosolutions is the leading supplier of Human APO TRANSFERRIN from human serum for use in cell culture, medical research, manufacturing of clinical diagnostic assays for iron deficiencies and disorders of the immune system. Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.

Purification procedures include selective size exclusion, ion exchange chromatography and gel filtration for transferrin products.

Transferrin products we offer:
535-12 - Human APO TRANSFERRIN from Human Serum
535-50 - Rat APO TRANSFERRIN from Rat Serum
535-11 - Human HOLO TRANSFERRIN (TF) from Human Serum
CTX-80A - Transferrin, Polyclonal Chicken anti-Human Affinity Purified Antibody


Human Transferrin is offered as a lyophilized powder in both Apo (iron-free) and Holo (iron-saturated) forms. Human APO Tranferrin is iron saturated. Each Human transferrin molecule binds with two Fe3+ ions to form a reddish complex and is a serum protein involved in iron binding and transport. APO Human Transferrin is Substantially iron-free.

Human apo Transferrin ANALYSIS: Total protein determination by the Lowry method. SDS-Polyacrylamide gel electrophoresis shows one major band only corresponding to the molecular weight of Transferrin.

Human Transferrin is a plasma protein for iron ion delivery. Human Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron binding domains. Human Transferrin is related to other iron binding proteins including lactoferrin. When human transferrin loaded with iron encounters a human transferrin receptor on the surface of a cell, it binds to it and is consequently transported into the cell in a vesicle. The cell will acidify the vesicle, causing human transferrin to release its iron ions. Each human transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+).

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