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Item #: 535-12
Siderophilin, TRF,apo-hTF , apotransferrin
Light Pink Powder
>99% by SDS-PAGE
< 30 ppm
IN STOCK - Ships same day
Lyophilized in Ammonium Bicarbonate buffer, pH 7.2
< 1 EU/mg
Lee Biosolutions is the leading supplier of Human APO TRANSFERRIN from human serum for use in cell culture, medical research, manufacturing of clinical diagnostic assays for iron deficiencies and disorders of the immune system. Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Purification procedures include selective size exclusion, ion exchange chromatography and gel filtration for transferrin products.
Transferrin products we offer:
535-12 - Human APO TRANSFERRIN from Human Serum
535-50 - Rat APO TRANSFERRIN from Rat Serum
535-11 - Human HOLO TRANSFERRIN (TF) from Human Serum
CTX-80A - Transferrin, Polyclonal Chicken anti-Human Affinity Purified Antibody
Human Transferrin is offered as a lyophilized powder in both Apo (iron-free) and Holo (iron-saturated) forms. Human APO Tranferrin is iron saturated. Each Human transferrin molecule binds with two Fe3+ ions to form a reddish complex and is a serum protein involved in iron binding and transport. APO Human Transferrin is Substantially iron-free.
Human apo Transferrin ANALYSIS: Total protein determination by the Lowry method. SDS-Polyacrylamide gel electrophoresis shows one major band only corresponding to the molecular weight of Transferrin.
Human Transferrin is a plasma protein for iron ion delivery. Human Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron binding domains. Human Transferrin is related to other iron binding proteins including lactoferrin. When human transferrin loaded with iron encounters a human transferrin receptor on the surface of a cell, it binds to it and is consequently transported into the cell in a vesicle. The cell will acidify the vesicle, causing human transferrin to release its iron ions. Each human transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+).