Item#: 900-20R PROLACTIN, Human (Recombinant)

Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a varaiety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of the reporductive functions and immunoregulation.

Recombinant prolactin comprises of 199 amino acid fragment (29-227) corresponding to the mature prolactin protein and is expressed in E. coli with an amino-terminal hexahistidine tag.

Human Prolactin research:
Elevated prolactin serum levels and history of alcohol withdrawal seizures. ref:Journal of Psychiatric Research, Volume 41, Issue 8, October 2007, Pages 702-706

Human Prolactin Research:
Reproductive experience modifies dopaminergic function, serum levels of prolactin, and macrophage activity in female rats. Prolactin ref:Life Sciences, Volume 81, Issue 2, 20 June 2007, Pages 128-136

Human Prolactin Research:
Prolactin secretory surge during estrus coincides with increased dopamine activity in the hypothalamus and preoptic area and is not altered by ovariectomy on proestrus. ref: Brain Research Bulletin, Volume 73, Issues 1-3, 15 June 2007, Pages 127-13