Item#: 510-11PR Prorenin Human ( recombinant )
Product Info:
Print This Page (Macintosh users, select "Print" from your browser's "File" menu)
| Product Name: | Prorenin Human ( recombinant ) |
|---|---|
| Cat. No: | 510-11PR |
| Form: | Liquid in 50 mM Tris pH 8.0 |
| Molecular Weight: | 45kd |
| Purity: | > 99% Pure by SDS Page: crystallographic grade |
| Source: | HEK Cells-Recombinant |
| Storage: | -20C |
Recombinant Human Prorenin bulk quantities from 1-100mg single lot sizes. Custom fills for recombinant human prorenin available.
Recombinant human prorenin(pro-renin) is expressed in HEK cells
Human RENIN and Human Prorenin products we offer
510-11PR Recombinant Human Prorenin Human
510-11 Native Human RENIN
510-11R Recombinant Human Renin Human
Human Prorenin study: Prorenin is the inactive precursor of renin, which is a key enzyme in the regulation of blood pressure and electrolyte balance. In renal juxtaglomerular cells, sequential cleavage of the N-terminal 20 and 46 amino acids of preprorenin produces prorenin and active renin, respectively. Human Prorenin REF: Journal of Protein Chemistry 9(6) 663-672 (1990)/prorenin.
Human prorenin study: Prorenin Levels in Retinopathy of Prematurity. Human prorenin ref:American Journal of Ophthalmology, Volume 143, Issue 3, March 2007, Pages 531-533/prorenin
recombinant human prorenin research: Using pure recombinant human prorenin as a substrate, we have identified an enzyme in human kidney that accurately processes prorenin to active renin.recombinant human prorenin REf:Proc Natl Acad Sci U S A. 1990 March; 87(5): 1927–1931/prorenin
Human prorenin study: Abnormal prorenin processing in growth hormone deficiency. Human prorenin ref:Growth Hormone & IGF Research, Volume 15, Issue 4, August 2005, Pages 251-255/prorenin
Human Prorenin (pro-renin)Research:
Although the prorenin does not contain renin, prorenin does display a low level (<5%) of renin activity that is intrinsic to the zymogena. Human Prorenin ref: Heinrikson R. L. et al. (1989) Amer. Jour. Hyperten. 2:367-380/prorenin
Human prorenin study:Human Prorenin: Human Renin is synthesized as an enzymatically inactive prorenin, which is split by limited proteolysis to give the active renin enzyme. Both human renin and human prorenin is secreted by the kidney(s). Circulating human renin concentrations are occasionally raised in nephroblastoma. Human Prorenin Ref: Plasma Renin activity in Wilms Tumor. 1971,67:197-202/prorenin.
Human Prorenin study: Role of Nonproteolytically Activated Prorenin (pro-renin)in Pathologic, but Not Physiologic, Retinal Neovascularization Human Prorenin REF: Investigative Ophthalmology and Visual Science. 2007;48:422-429/prorenin
Human prorenin study: Human prorenin(pro-renin) is a marker of Wilms tumor. Human Prorenin Ref: Journal of Clinical Endocrinology and Metabolism. Vol. 79, No. 6, 1994/prorenin
Human prorenin research:Raised prorenin and renin concentrations in pre-eclamptic placentae when measured after acid activation.Human prorenin ref:Placenta, Volume 25, Issue 7, August 2004, Pages 631-636/prorenin
Human prorenin research:Prorenin Uptake in the Heart: a Prerequisite for Local Angiotensin Generation?Human prorenin ref:Journal of Molecular and Cellular Cardiology, Volume 34, Issue 11, November 2002, Pages 1463-147/prorenin
Human prorenin study: Prorenin and the (pro)renin receptor—an update: Human Prorenin REF: Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfl846/prorenin
uman prorenin research: Human seminal fluid contains significant quantities of prorenin: its correlation with the sperm density. human prorenin REF:
Molecular and Cellular Endocrinology, Volume 109, Issue 2, 1 April 1995, Pages 219-224/prorenin
human prorenin research: Protein modeling of human prorenin using the molecular dynamics methods.human prorenin REF: Journal of Molecular Graphics,Volume 8 , Issue 3 (September 1990),Pages: 163 - 167 /prorenin
Human prorenin ref:Prorenin and the (pro)renin receptor—an update. Human Prorenin REF: Nephrology Dialysis Transplantation, doi: 10.1093 /ndt/gfl846 /prorenin
What is human prorenin article: Human prorenin is the enzymatically inactive biosynthetic precursor of renin. Human Prorenin Reference:Hypertension, Vol 17, 469-477/prorenin
human prorenin research: Uptake and intracellular activation of prorenin in human endothelial cells.human prorenin REF: American Journal of Hypertension, Volume 8, Issue 4, Part 2, April 1995, Page 42A/prorenin
Renin Research: Effect of upregulated renin–angiotensin system on per2 and bmal1 gene expression in brain structures involved in blood pressure control in TGR(mREN-2)27 rats.Renin Ref:Brain Research, Volume 1180, 14 November 2007, Pages 29-38/renin
Renin Research:The (pro)renin receptor: A new addition to the renin–angiotensin system?European Journal of Pharmacology, Volume 585, Issues 2-3, 13 May 2008, Pages 320-324/renin/pro-renin/renin study
Renin Research:From Black and White to Shades of Gray: Race and Renin-Angiotensin System Blockade,Journal of the American College of Cardiology, Volume 51, Issue 19, 13 May 2008, Pages 1872-1873/renin/pro-renin/renin study
Renin Research:Renin angiotensin system blockade and cardiovascular outcomes in patients with chronic kidney disease and proteinuria: A meta-analysis
American Heart Journal, Volume 155, Issue 5, May 2008, Pages 791-805/renin/pro-renin/renin study
Renin Research:Potential role of Renin–Angiotensin-system for tumor angiogenesis in receptor negative breast cancer.Gynecologic Oncology, 18 April 2008/renin/pro-renin/renin study
Renin Research:Inhibition of renin angiotensin system decreases renal protein oxidative damage in diabetic rats,Biochemical and Biophysical Research Communications, Volume 368, Issue 3, 11 April 2008, Pages 528-535/renin/pro-renin/renin study
Renin Research:Outcomes of Acute Kidney Injury Associated With Inhibitors of Renin-Angiotensin System,American Journal of Kidney Diseases, Volume 51, Issue 4, April 2008, Page B47/renin/pro-renin/renin study
Renin Research:Critical roles of (pro)renin receptor-bound prorenin in diabetes and hypertension: sallies into therapeutic approach,Journal of the American Society of Hypertension, Volume 2, Issue 1, January-February 2008, Pages 15-19/renin/pro-renin/renin study
Renin Research:Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes. Journal of Psychosomatic Research, Volume 62, Issue 6, June 2007, Pages 703-706/renin/pro-renin/renin study