We Are Solutions...On Demand
We Are Solutions...On Demand
Item #: 497-50
pH:
6.0
Catalogue Number:
497-50
Recertification:
2 years
Product Name:
Proteinase 3
Storage:
Below -20 C Long-Term
Availability:
IN STOCK - Ships same day
Synonyms:
PR3 Ag, PR3, PR III, Myoblastin
Activity:
Typically >0.1 U/mg protein
Protein:
Typically >0.5 mg protein/mL by BCA
Form:
Solution in 0.05 M sodium acetate, 0.7 M sodium chloride
Purity:
>96% by SDS-PAGE, Identity confirmed by Western Blot
Source:
Human Neutrophils
CAS Number:
128028-50-2
E.C. Number:
3.4.21.76
Lee Biosolutions is the leading supplier of Human PROTEINASE 3 (PR-3) for research and diagnostic manufacturing.
Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Current Research suggests that PR3 may represent a clinically useful marker of prognosis after an AMI as part of a multimarker strategy. It is the major target antigen of antineutrophil cytoplasmic autoantibodies (ANCA) in Wegener's granulomatosis and is contained in the azurophilic granules of polymorphonuclear neutrophils, the dominant cell type in vascular lesions during the early stages of systemic vasculitis.
Unit Definition: One unit will hydrolize one micromole of Methoxy succinyl-alanine-alanine-proline-valine-p-nitroanilide per minute at 37C and pH 7.5
Lee Biosolutions, Inc specializes in the development and purification of high quality BioMarkers for the Immunodiagnostic, clinical diagnostic and pharmaceutical industry worldwide.
