We Are Solutions...On Demand

Youtube Facebook Twitter LinkedIn

Human Neutrophil Proteinase 3 (PR3) - ANCA

Sort By: All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Item #: 497-50

Description

pH:

6.0

Recertification:

2 years

Catalogue Number:

497-50

Storage:

Below -20 C Long-Term

Purity:

>96% (SDS-PAGE, Identity confirmed by Western Blot)

Protein:

Typically >0.5 mg protein/mL by BCA

Form:

Solution in 0.05 M sodium acetate, 0.7 M sodium chloride

E.C. Number:

3.4.21.76

Synonyms:

PR3 Ag, PR3, PR III, Myoblastin

Product Name:

Proteinase 3

Source:

Human Neutrophils

CAS Number:

128028-50-2

Activity:

Typically >0.1 U/mg protein

Price

Unit

Qty

Details

Lee Biosolutions is the leading supplier of Human PROTEINASE 3 (PR-3) for research and diagnostic manufacturing.

Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.

Current Research suggests that PR3 may represent a clinically useful marker of prognosis after an AMI as part of a multimarker strategy. It is the major target antigen of antineutrophil cytoplasmic autoantibodies (ANCA) in Wegener's granulomatosis and is contained in the azurophilic granules of polymorphonuclear neutrophils, the dominant cell type in vascular lesions during the early stages of systemic vasculitis.

Unit Definition: One unit will hydrolize one micromole of Methoxy succinyl-alanine-alanine-proline-valine-p-nitroanilide per minute at 37C and pH 7.5

Questions

About A Product?

Click Here

Talk with our scientific experts today.

More