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Item #: 191-27R3
Activity:
Typically > 400 u/ml@ 37C
Source:
Pichia Pastoris
Protein:
Typically > 1mg/ml
Storage:
-70C Recommended
Form:
50% Glycerol and Tris buffer
Purity:
> 90% by Capillary Electrophoresis
Synonyms:
r-hCKMM III,
BULK QUANTITIES of recombinant human CREATINE KINASE MM, CKMM isoenzyme from 50 - 1000mgs single lot sizes
Recombinant full length Creatine Kinase MM Isoenzyme with amino acid sequence exactly the same as the native enzyme. Purified in the enzymatically active form. Reacts with polyclonal antibodies to MM isoenzyme in ELISA. CKMM is a 47 kDa dimeric protein comprised of two identical M subunits, produced in Pichia pastoris, and purified under non-denaturing conditions.
Background: Human Creatine phosphokinase (CK)CPK isoenzymes are performed when the total human CPK level is elevated. Human CK(CPK)Isoenzyme testing can help differentiate the source of the damaged tissue. Human (CPK)CK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Human (CKMM)CK-MM, Human (CKBB)CK-BB isoenzyme and Human (CKMB)CK-MB isoenzyme exist.
Human creatine kinase (CK-MM)CKMM isoenzyme research:Identification of a CKMM-IgA complex in the serum of a child with Duchenne Muscular Dystrophy. Human creatine kinase (CK-MM)CKMM isoenzyme REF: MA Pesce - ITALIAN JOURNAL OF PEDIATRICS, 2002 - PACINIEDITORE/human/isoenzyme/creatine kinase