HUMAN PSA-ACT COMPLEX

• High Purity Proteins
• Recombinant Proteins
• Antibodies
• Biologicals
• Fine Biochemicals
• Reagents

Item #: 498-11

Details

Human PSA-ACT COMPLEX: Free-PSA has a molecular weight of 28 kDa and a pI of 6.2-6.5, while PSA-ACT molecular weight is 90 kDa (PSA 28KDa and ACT 60-65KDa). Prostate Specific Antigen PSA is localised in cytoplasm of prostate acinar cells, ductal epithelium and seminal fluid. Prostate Specific Antigen PSA exists in 3 major forms; free PSA, PSA-ACT (PSA bound to Alpha-1 Antichymotrypsin) and PSA-A2M (PSA bound to Alpha-2 Macroglobulin). Serum concentration as a free to bound ratio correlates well with tumour mass and clinical stage of prostate cancer. High levels of free PSA can also be seen in serum from patients with benign hypertrophy

PSA related products offered by Lee Biosolutions:
497-11 Prostate Specific Antigen Human (PSA)
498-11 PSA-ACT Complex Human
991-04 Human Semen
CPSA-80A Prostate Specific Antigen Polyclonal Anti-human Affinity Purified

Human PSA-ACT COMPLEX BULK QUANTITIES from 1 -25 mg single lot sizes

Human PSA-ACT Complex research:
measurement of free PSA and the PSA-ACT complex may improve the utility of the serum PSA assay for differential diagnosis of prostate cancer and non-malignant prostate diseases. Human PSA-ACT Complex REF: Prostate. 2003 Jul 1;56(2):131-41/human/psa/act/complex/cancer

Human PSA-ACT Complex research Usefulness of human alpha 1-antichymotrypsin-PSA complex (human PSA-ACT complex) for predicting bone metastases of prostate cancer:Human PSA-ACT Complex REF: Urology. 2006 Aug;68(2):371-5/human/psa/act/complex/cancer

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