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Item #: 527-20
Source:
Human Serum
Storage:
2-8 C
UNSPSC code:
51131907
Cat. No:
527-20
Form:
Liquid in .01M Tris Buffer pH 8.0, .015M NaCl, .01M EDTA
STOCK STATUS:
LEAD TIME REQUIRED
Molecular Weight:
250kDa
Purity:
Greater than 96% by SDS Page
LEAD TIME REQUIRED:
Human Serum Amyloid P (Human SAP) Bulk quantities from 100-500mgs. Custom fills of Human Serum Amyloid P (SAP)available. Inquire on custom buffers of Human Serum Amyloid P (SAP)on bulk orders.
Human Serum Amyloid P is a small, non-fibrillar glycoprotein found in normal serum and in all amyloid deposits. Human Serum Amyloid P (SAP) has a pentagonal structure. Human Serum Amyloid P (SAP) modulates immunologic responses in man, inhibits elastase and has been suggested as an indicator of liver disease.
Human Serum Amyloid P (SAP) is a member of the pentraxin family, characterised by calcium dependent ligand binding and distinctive flattened â-jellyroll structure similar to that of the legume lectins (Emsley J. et al, 1994). Serum Amyloid P component (SAP) is the identical serum form of Amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid" (Cathcart et al, 1967).
Human Serum Amyloid P (SAP) has 51% sequence homology with C-reactive protein (CRP),
Human Serum Amyloid P (Human SAP) research: Serum amyloid P component induces TUNEL-positive nuclei in rat brain after intrahippocampal administration.Human Serum Amyloid P (Human SAP) REF:Brain Research, Volume 1145, 11 May 2007, Pages 221-226/human/serum/amyloid/p