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HUMAN SERUM AMYLOID P (HUMAN SAP) - HIGH PURITY

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Item #: 527-20

Description

Source:

Human Serum

Storage:

2-8 C

UNSPSC code:

51131907

Cat. No:

527-20

Form:

Liquid in .01M Tris Buffer pH 8.0, .015M NaCl, .01M EDTA

STOCK STATUS:

LEAD TIME REQUIRED

Molecular Weight:

250kDa

Purity:

Greater than 96% by SDS Page

Price

Unit

Qty

$500.00

mg

$185.00

250ug

Details

LEAD TIME REQUIRED:
Human Serum Amyloid P (Human SAP) Bulk quantities from 100-500mgs. Custom fills of Human Serum Amyloid P (SAP)available. Inquire on custom buffers of Human Serum Amyloid P (SAP)on bulk orders.

Human Serum Amyloid P is a small, non-fibrillar glycoprotein found in normal serum and in all amyloid deposits. Human Serum Amyloid P (SAP) has a pentagonal structure. Human Serum Amyloid P (SAP) modulates immunologic responses in man, inhibits elastase and has been suggested as an indicator of liver disease.

Human Serum Amyloid P (SAP) is a member of the pentraxin family, characterised by calcium dependent ligand binding and distinctive flattened â-jellyroll structure similar to that of the legume lectins (Emsley J. et al, 1994). Serum Amyloid P component (SAP) is the identical serum form of Amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid" (Cathcart et al, 1967).

Human Serum Amyloid P (SAP) has 51% sequence homology with C-reactive protein (CRP),


Human Serum Amyloid P (Human SAP) research: Serum amyloid P component induces TUNEL-positive nuclei in rat brain after intrahippocampal administration.Human Serum Amyloid P (Human SAP) REF:Brain Research, Volume 1145, 11 May 2007, Pages 221-226/human/serum/amyloid/p

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