Item#: 527-20 Serum Amyloid P(SAP) Human
Product Info:
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| Product Name: | Serum Amyloid P(SAP) Human |
|---|---|
| Cat. No: | 527-20 |
| Form: | Liquid in .01M Tris Buffer pH 8.0, .015M NaCl, .01M EDTA |
| Molecular Weight: | 250kDa |
| Purity: | greater than 96% by SDS Page |
| Source: | Human Serum |
| Storage: | 2-8C |
| UNSPSC code: | 51131907 |
Human Serum Amyloid P (Human SAP) Bulk quantities from 100-500mgs. Custom fills of Human Serum Amyloid P (SAP)available. Inquire on custom buffers of Human Serum Amyloid P (SAP)on bulk orders.
Human Serum Amyloid P is a small, non-fibrillar glycoprotein found in normal serum and in all amyloid deposits. Human Serum Amyloid P (SAP) has a pentagonal structure. Human Serum Amyloid P (SAP) modulates immunologic responses in man, inhibits elastase and has been suggested as an indicator of liver disease.
Human Serum Amyloid P (SAP) is a member of the pentraxin family, characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins (Emsley J. et al, 1994). Serum Amyloid P component (SAP) is the identical serum form of Amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid" (Cathcart et al, 1967).
Human Serum Amyloid P (SAP) has 51% sequence homology with C-reactive protein (CRP),
Human Serum Amyloid P (Human SAP) research: Serum amyloid P component induces TUNEL-positive nuclei in rat brain after intrahippocampal administration.Human Serum Amyloid P (Human SAP) REF:Brain Research, Volume 1145, 11 May 2007, Pages 221-226/human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research: Serum amyloid P (SAP) inhibits dermal wound healing.Human Serum Amyloid P (Human SAP) Ref:
Journal of Surgical Research, Volume 137, Issue 2, February 2007, Page 231/human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research: Evidence for an extended interacting surface between β-amyloid and serum amyloid P component.Human Serum Amyloid P (Human SAP) Ref:
Neuroscience Letters, Volume 412, Issue 1, 22 January 2007, Pages 51-55/human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research:Serum Amyloid P and Cardiovascular Disease in Older Men and Women.Human Serum Amyloid P (Human SAP) Ref:Arteriosclerosis, Thrombosis, and Vascular Biology. 2007;27:352/human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research:Proteomic analysis of UVC irradiation-induced damage of plasma proteins: Serum amyloid P component as a major target of photolysis.Human Serum Amyloid P (Human SAP) Ref:
FEBS Letters, Volume 580, Issue 13, 29 May 2006, Pages 3229-3236/human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research:Serum amyloid P-component in murine tuberculosis: induction kinetics and intramacrophage Mycobacterium tuberculosis growth inhibition in vitro.Human Serum Amyloid P (Human SAP) Ref:Microbes and Infection, Volume 8, Issue 2, February 2006, Pages 541-551/human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research:Glycosaminoglycans inhibit neurodegenerative effects of serum amyloid P component in vitro.Human Serum Amyloid P (Human SAP) Ref:
Neurochemistry International, Volume 46, Issue 6, May 2005, Pages 471-477/human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research:Binding of Ca2+, Mg2+, and heparin by human serum amyloid P component in affinity capillary electrophoresis.Human Serum Amyloid P (Human SAP) Ref: ELECTROPHORESIS June 2006 Volume 27, Issue 13 ,Pages 2609-2615/human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research:Human Serum Amyloid P Component Binds to Peripheral Blood Monocytes.Human Serum Amyloid P (Human SAP) Ref:Scandinavian Journal of Immunology Vollume 64 Issue 1 Page 48 - July 2006 /human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research:Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis. Human Serum Amyloid P (Human SAP) Ref: Nature 417, 254-259 (16 May 2002)/human/serum/amyloid/p
Human Serum Amyloid P (Human SAP) Research: Quantification of serum amyloid P by enzyme-linked immunosorbent assay. Human Serum Amyloid P (Human SAP) Ref:Clin. Chem., Oct 1991; 37: 1742 - 1745/human/serum/amyloid/p