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Item #: 342-40
Synonyms:
ELA-2, HNE, neg
EC No:
3.4.21.37
Protein:
Typically > 1mg/ml
Cat. No:
342-40
Source:
Human Neutrophil
Activity:
Typically >10 u/ml @ 37C
Expiration:
1 year
Purity:
> 90% by SDS Page
UNSPSC code:
51131907
Form:
50 mM sodium acetate, pH 5.5, 0.6 M sodium chloride
Storage:
2-8 C
HUMAN ELASTASE from Neutrophil(s) BULK QUANTITIES from 50-300mg. Custom fills for Human Neutrophil Elastase availble. Custom buffers for Human Neutrophil elastase on bulk orders.
Human Neutrophil(s), also known as neutrophilic polymorphonuclear leukocytes, are the major class of white blood cell in human peripheral blood. Human Neutrophil(s), have a multilobed nucleus and neutrophilic granules. Neutrophil(s) are phagocytes and have an important role in engulfing and killing extracellular pathogens.
Neutrophil elastase (NE) is a key enzyme for tissue injury caused by activated neutrophils, such as occurs in Acute Lung injury.
The neutrophil form of elastase is 218 amino acids long, with two asparagine-linked carbohydrate chains.
Neutrophil elastase UNIT DEFINITION: One unit will hydrolyze one micromole of Methoxy succinyl-alanine-alanine-proline-valine-p-nitroanilide per minute at 37C and pH 7.5
Human Neutrophil elastase research: Neutrophil elastase and cancer.Human Neutrophil elastase ref:Surgical Oncology, 22 February 2007/elastase/neutrophil(s)
Human Neutrophil elastase research: Association of plasma neutrophil elastase levels with other inflammatory mediators and clinical features in adult patients with moderate and severe pneumonia.Human Neutrophil elastase ref: