Chicken RECOMBINANT LACATE DEHYDROGENASE (LDH)

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Item #: 350-50R

Details

Recombinant Chicken heart LDH Bulk quantities available in 1-10 million unit single lot sizes.

Native chicken heart LDH available at 350-50.

Lactate dehydrogenase (LDH) is an enzyme (EC 1.1.1.27) present in a wide variety of organisms, including plants and animals. Lactate Dehydrogenase (LDH) catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. Lactate Dehydrogenase(LDH) can also catalyze the oxidation of hydroxybutyrate, it is occasionally called Hydroxybutyrate Dehydrogenase (HBD).

Meningitis and encephalitis
The enzyme is also found in cerebrospinal fluid where high levels of lactate dehydrogenase in cerebrospinal fluid are often associated with bacterial meningitis. High levels of the enzyme can also be found in cases of viral meningitis, generally indicating the presence of encephalitis and poor prognosis.
HIV and elevated LDH.

LDH is often measured in HIV patients as a non-specific marker for Pneumocystis jiroveci (formerly Pneumocystis carinii) pneumonia (PCP). Elevated LDH in the setting of upper respiratory symptoms in an HIV patient suggests, but is not diagnostic for, PCP.

Porcine Lactate Dehydrogenase research:
BABAB elementary supersecondary structure of the Rossmann fold from porcine lactate dehydrogenase exhibits characteristics of a molten globule. Lactate Dehydrogenase LDH REF:Proteins: Structure, Function, and Bioinformatics Volume 60,Issue 4 ,Pages 740-745

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