Item#: 528-50 THROMBIN (alpha) Bovine
Product Info:
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| Product Name: | THROMBIN (alpha) Bovine |
|---|---|
| CAS No: | 9002-04-4 |
| Cat. No: | 528-50 |
| EC No: | 3.4.21.5 |
| Expiration: | 5 years |
| Form: | Lyophilized |
| Molecular Weight: | 36000 |
| Source: | Bovine Plasma |
| Specific Activity: | > 100 NIH units/mg protein |
| Storage: | -20 C |
BOVINE THROMBIN bulk quantities from 50-250 million unit single lot sizes. Custom fills available for Bovine Thrombin(alpha).
Bovine Thrombin EC 3.4.21.5 (activated Factor II) is a coagulation protein that has many effects in the coagulation cascade. Bovine Thrombin is a serine protease that converts fibrinogen into fibrin.
Bovine Thrombin used as a reagent, Thrombin has proven useful in the laboratory evaluation of many fibrinogen(s)
Coagulation proteins that we offer
314-15 Human KALLIKREIN
314-10 Porcine KALLIKREIN
494-10 Porcine PROTHROMBIN
528-50 bovine THROMBIN
528-50H High Activity Bovine Thrombin
528-70 Human THROMBIN
528-60 Porcine THROMBIN
Our customers use Bovine Thrombin to defibrinate human plasma, producing serum matrixes to be used as controls and standards. Bovine Thrombin High specific material Cat. NO: 528-50 available (> 2000 U/mg protein) is used to cleave r-fusion proteins containing a thrombin site for removal of affinity tags as well as certain diagnostic pharmaceutical applications.
Thrombin promotes chemotaxis in monocytes, neurite retraction in neuron Thrombin serves as a potent mitogenic agent in fibroblast growth and functions as a serum-free media component for several cell lines
Bovine Thrombin is a multifunctional proteolytic' enzyme which acts both specifically and non-specifically with several proteins, cells, surfaces, and other molecules. Bovine Thrombin(s) essential role in the clotting process has been well characterized where it converts fibrinogen, a soluble plasma glycoprotein, to an insoluble protein gel called fibrin, the essential component of the blood clot.
Bovine Thrombin is a clotting enzyme that is a serine protease which cleaves Arginine-Glycine bonds in fibrinogen to give clots of fibrin & fibrinpeptide A and B. Bovine Thrombin is derived from bovine prothrombin which is isolated from bovine plasma. Bovine prothrombin is treated with bovine lung thromboplastin to yield Bovine Thrombin.
Thrombin is also used to remove GST tags from proteins in purification process.
Effect of liver damage on the level of coagulation factor II, X and VII in human and bovine plasma.Thrombosis Research. 1988 Oct 15;52(2):79-85/bovine/thrombin.
Thrombin Research: The binding of human and bovine thrombin to human platelets Research Study: Human thrombin binds to specific receptors on the surface of human platelets in a manner analogous to bovine thrombin. bovine Thrombin REF: Volume 47, Issue 1, pp. 43-54, 01/01/1976 The American Society of Hematology/bovine/thrombin.
bovine thrombin research: Influence of freeze-drying on the clotting properties of fibrinogen in plasma. bovine Thrombin REF: Thrombosis Research Volume 105, Issue 6, 15 March 2002, Pages 499-502/bovine/thrombin.
The binding of human and bovine thrombin to human platelets Research Study: Human thrombin binds to specific receptors on the surface of human platelets in a manner analogous to bovine thrombin. bovine Thrombin REF: Volume 47, Issue 1, pp. 43-54, 01/01/1976 The American Society of Hematology/bovine/thrombin.
bovine thrombin research: Influence of freeze-drying on the clotting properties of fibrinogen in plasma. bovine Thrombin REF: Thrombosis Research Volume 105, Issue 6, 15 March 2002, Pages 499-502/bovine/thrombin.
Bovine thrombin study: Evaluation of the clotting time of bovine thrombin, reptilase and thrombin-like fraction of Crotalus durissus terrificus venom using cryoprecipitate from humans and different animals. bovine Thrombin REF: Toxicon, Volume 38, Issue 4, April 2000, Page 576/bovine/thrombin.
Thrombin factor IIa research: Steady state relations between factors X, Xa, II, IIa, antithrombin III and alpha-2 macroglobulin in thrombosis. Thrombin REF: Thrombosis Research, Volume 18, Issues 1-2, 1-15 April 1980, Pages 19-31/bovine/thrombin.
bovine Thrombin research: Antihuman Factor V Antibodies After Use of Relatively Pure Bovine Thrombin. bovine Thrombin REF: Ann Thorac Surg 2005;79:1037-1038/bovine/thrombin.
bovine Thrombin research:RNA aptamers specific for bovine thrombin.bovine Thrombin ref: Journal of molecular recognition, 2003,vol.16,pp. 23-27/bovine/thrombin.
bovine Thrombin research: Bovine thrombin complexed with an uncleavable analog of residues 7-19 of fibrinogen A alpha.bovine Thrombin ref: Biochemistry 35 (40), 13030-13039 1996/bovine/thrombin.
bovine Thrombin research:Crystal structure of bovinethrombin-ecotin reveals conformational changesand extended interactions.bovine Thrombin reference: Biochemistry 40 (34), 10038-10046 (2001)/bovine/thrombin.
Coagulation proteins that we offer
314-15 KALLIKREIN - Human Urine
314-10 KALLIKREIN - Porcine Pancreas
494-10 PROTHROMBIN Porcine
528-50 THROMBIN (alpha) Bovine
528-70 THROMBIN (alpha) Human
528-60 THROMBIN (alpha) Porcine
Lee Biosolutions Bovine Thrombin is not to be used for any human therapeutic use. bovine Thrombin Articles are for informational purposes only.
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