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Item #: 560-11R
Protein:
Typically >.5mg/ml
Storage:
< -50C
Expiration:
1 year
Cat. No:
560-11R
Form:
Glycerol and tris buffer
Purity:
>96% by SDS Page
Source:
Recombinant
Synonyms:
r-hTPO, r-TPO,TPO
Molecular Weight:
97kDa
Human Thyroid peroxidase (TPO) is an enzyme mainly expressed in the thyroid that liberates iodine for addition onto tyrosine residues on thyroglobulin for the production of thyroxine (thyroid hormone)
human Thyroid Peroxidase (TPO) is the antigenic determinant of the thyroid microsome associated with anti-TPO autoantibodies. Anti-TPO is an important secondary marker in the diagnosis of Grave's and Hashimoto disease. Thyroid antibodies are also assiciated with infertility and fetal loss
Human recombinant Thyroid Peroxidase available in bulk quantities from 25-100mg. Custom fills available for recombinant human thyroid peroxidase.
Elevated Thyroid Peroxidase Antibodies with Encephalopathy in MELAS Syndrome
Pediatric Neurology, Volume 36, Issue 6, June 2007, Pages 414-417/human/thyroid/peroxidase/recombinant
Human Thyroid Peroxidase research:Performance characteristics of 5 automated thyroglobulin autoantibody and thyroid peroxidase autoantibody assays.Human Thyroid Peroxidase ref:Clinica Chimica Acta, Volume 376, Issues 1-2, 1 February 2007, Pages 88-95/human/thyroid/peroxidase/recombinant
Human Thyroid Peroxidase research:Protein radical formation on thyroid peroxidase during turnover as detected by immuno-spin trapping.