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Pepsinogen I (PGI, PGA)

Description

Product Name Pepsinogen I
Source Human Gastric Mucosa
Catalogue Number 440-01
Availability Discontinued, replaced with item 440-50
Purity > 90% (SDS-PAGE)
Identity Confirmed by Western Blot
Protein > 0.5 mg/mL (A280, E0.1%=1.48)
Form Liquid
Recertification 1 year
Storage 2-8°C
Molecular Weight 45 kDa
Synonyms Pepsinogen A, PG1, PGA
UNSPSC code 51131907
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Lee Biosolutions is the leading producer and supplier of human gastric Pepsinogen I (A) antigen as a cancer marker for medical research, clinical and biomedical manufacturing.

Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.

Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II).

Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis.

It has been reported that human Pepsinogen I (PGA)levels were lower in atrophic corpus gastritis than in atrophic antral gastritis, and human pepsinogen I(PGA) levels were lower in advanced gastric cancer than early stage gastric cancer.

Diagnostic Controls, Calibrators & Standards

Testing/Assay Validation

Life Science

ELISA, Blotting, Etc.

Tumor Markers