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Pepsinogen I (PGI, PGA)


Product Name Pepsinogen I
Source Human Gastric Mucosa
Catalogue Number 440-01
Availability Discontinued, replaced with item 440-50
Purity > 90% (SDS-PAGE)
Identity Confirmed by Western Blot
Protein > 0.5 mg/mL (A280, E0.1%=1.48)
Form Liquid
Recertification 1 year
Storage 2-8°C
Molecular Weight 45 kDa
Synonyms Pepsinogen A, PG1, PGA
UNSPSC code 51131907


Diagnostic Controls, Calibrators & Standards

Testing/Assay Validation

Life Science

ELISA, Blotting, Etc.

Tumor Markers


Lee Biosolutions is the leading producer and supplier of human gastric Pepsinogen I (A) antigen as a cancer marker for medical research, clinical and biomedical manufacturing.

Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.

Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II).

Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis.

It has been reported that human Pepsinogen I (PGA)levels were lower in atrophic corpus gastritis than in atrophic antral gastritis, and human pepsinogen I(PGA) levels were lower in advanced gastric cancer than early stage gastric cancer.

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