Pepsinogen II (PGII, PGC)
|Product Name||Pepsinogen II|
|Source||Human Gastric Mucosa|
|Purity||> 90% (SDS-PAGE)|
|Identity||Confirmed by Western Blot|
|Protein||> 0.5 mg/mL (A280, E0.1%=1.48)|
|Activity||Reported (after activation)|
|Unit Definition||One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.|
|Synonyms||Pepsinogen C, PG II, PGC, Gastricsin|
|Molecular Weight||40 kDa|
Lee Biosolutions is the leading producer and supplier of Human Pepsinogen II/C antigen as a stomach gastric cancer marker for medical research, clinical and diagnostic manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Human Pepsinogen(s) PG(s) are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. Pepsinogen is synthesized as isoymogens and are classified into two groups, I and II.