beta-Nicotinamide-Adenine Dinucleotide (NADH), Reduced Form - Disodium Salt

beta-Nicotinamide-Adenine Dinucleotide, Reduced Form (beta-NADH) disodium salt available in kg quantities from Lee Biosolutions.

Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.

Nicotinamide adenine dinucleotide, abbreviated NAD+, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups: with one nucleotide containing an adenine base, and the other containing nicotinamide.

In metabolism, NAD+ is involved in redox reactions, carrying electrons from one reaction to another. The coenzyme is therefore found in two forms in cells: NAD+ is an oxidizing agent – it accepts electrons from other molecules and becomes reduced, this reaction forms NADH, which can then be used as a reducing agent to donate electrons. These electron transfer reactions are the main function of NAD+. However, it is also used in other cellular processes, notably as a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications. Due to the importance of these functions, the enzymes involved in NAD+ metabolism are targets for drug discovery.

UV Spectral Analysis: Ratios at pH 10.0 A250/A260 (0.83 ± 0.03) A280/A260 (0.23 ± 0.02) A340/A260 (0.43 ± 0.01)

Extinction Coeffient at 260 nm: (14.4 ± 0.5) x 103 Extinction Coeffient at 340 nm: (6.3 ± 0.2) x 103

Unstable in acids, but relatively stable at pH 10-11.