Myeloperoxidase (MPO) Antigen - Isoform C

Catalogue Number: 426-10C
Product Name Myeloperoxidase Isoform C
Source Human Neutrophils
Catalogue Number 426-10C
Form Liquid
Purity > 96% (SDS-PAGE)
Protein 1.0 - 2.0 mg/mL (A280, E0.1%=1.45)
Activity Typically > 1,000 U/mg protein
Unit Definition One unit of Myeloperoxidase will catalyze the consumption of one micromole of hydrogen peroxide and the production of ¼ micromole of tetraguaiacol per minute at pH 7.0 and 25°C.
Formulation Solution in 50 mM sodium acetate, pH 6.0, 100 mM sodium chloride.
RZ Value > 0.8 (A430/A280)
Related Products 550-21 - Troponin T antigen from human heart
431-11 - Myoglobin antigen from human heart
426-10 - Myeloperoxidase antigen from human leukocytes
Storage 2-8°C
Recertification 2 years
Infectious Disease Testing Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV, HBsAg, HCV NAT, HIV-1 NAT and syphilis by FDA approved methods.
Synonyms MPO-C, MPOC
Molecular Weight 146,000
CAS Number 9003-99-0
E.C. Number
Gene MPO
Gene ID 4353
Accession No P05164

Lee Biosolutions is the largest primary manufacturer of Myeloperoxidase Isoform C (MPO-C) enzyme for medical research and diagnostic manufacturing globally. It has been successfully used in protein crystallization research.

Custom preparations, technical support, bulk quantities and aliquoting available, email for more details.

Rz is an abbreviation for Reinheitszahl (purity number). It is the ratio of absorbance at 430 nm (heme)/ 280 nm (total protein). It is a measure of the purity of the enzyme. Anything above 0.8 is highly pure.

MPO is a peroxidase enzyme occurs the most in neutrophil granulocytes (a subtype of white blood cells). It is a lysosomal protein stored in azurophilic granules of the neutrophil. Myeloperoxidase has a green heme pigment and is found in pus and some forms of mucus. It is recognized as an important factor in many inflammatory diseases such as cardiovascular and neurological diseases. MPO-specific imaging agents would thus be highly useful to diagnose early disease, monitor disease progression, and quantify treatment effects.

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