Prolactin (PRL)
Product Name | Prolactin |
Source | Human Pituitary Glands |
Catalogue Number | 996-40 |
Purity | > 50% (SDS-PAGE) |
Form | Lyophilized |
Protein | > 0.5 mg/mg solid |
Activity | > 12 IU/mg |
Contaminants | TSH: < 2.0% FSH: < 3.0% LH: < 2.0% hGH: < 4.0% |
Formulation | Lyophilized from 50 mM ammonium bicarbonate. |
Reconstitution | Neutral pH buffer of choice. Avoid extreme high and low pH |
Related Products | 996-11 - FSH antigen from human pituitary gland 996-31 - LH antigen from human pituitary gland 996-51 - TSH antigen from human pituitary gland |
Storage | -20°C |
Recertification | 5 years |
Infectious Disease Testing | Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV and HBsAg by FDA approved methods. |
Synonyms | Luteotropic Hormone, LTH, PRL |
Molecular Weight | ~23,000 |
CAS Number | 9002-62-4 |
Lee Biosolutions is a producer and supplier of human pituitary Prolactin .
FOR LABORATORY AND MANUFACTURING USE ONLY AND NOT FOR USE IN HUMANS
Technical support, bulk quantities and custom buffers and aliquoting available, email Info@leebio.com for more details.
Prolactin is an integral member of the immunoneuroendocronology network and appears to have a role in pathogenesis of autoimmune diseases.
Prolactin was discovered 80 years ago and is currently viewed by clinical endocrinologists as a hormone of pituitary origin, whose production is negatively controlled by dopamine, whose biological actions relate exclusively to lactation and reproductive functions, for which any genetic disorder is yet to be identified, and whose unique associated pathology is hyperprolactinemia, which is efficiently cured using dopamine agonists. REF: Endocrine Abstracts (2011) 26 MTE11
Prolactin levels may be ordered when a person has symptoms of a prolactinoma, such as unexplained headaches, visual impairment, and/or galactorrhea. Testing for prolactin may be ordered, along with other tests, when a woman is experiencing infertility or irregular menses or when a man has symptoms such as decreased libido, galactorrhea, or infertility. Prolactin levels are also often ordered in men as a follow-up to a low testosterone level.