Eosinophil Cationic Protein (ECP)
|Product Name||Eosinophil Cationic Protein|
|Purity||> 80% (SDS-PAGE)|
|Protein Conc||0.1 - 1.0 mg/mL (BCA)|
|Form||0.2 micron filtered solution in 50 mM sodium acetate, 200 mM sodium chloride, pH 4.7.|
|Appearance||Clear, colorless liquid|
|Synonyms||ECP, Ribonuclease 3, RNase 3|
|Molecular Weight||18-22kDa (3 glycosolated forms exists)|
|Gene||RNASE3, ECP, RNS3|
Lee Biosolutions is the leading supplier of human Eosinophil Cationic Protein (ECP) for research and diagnostic manufacturing purposes.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Human Eosinophil degranulation in airway tissues is thought to make significant contributions to the pathogenesis of asthma, nasal polyposis, allergic rhinitis, and eosinophilic pneumonia.
It also alters pulmonary surfactant structure and function in asthma and the proteins are critical in the pathogenesis of tropical pulmonary eosinophilia (TPE).
Human Eosinophils are also associated with other diseases of the respiratory tract. Respiratory syncytial virus (RSV) is an important respiratory pathogens worldwide. Infection is often implicated in exacerbation of asthma in children.