Butyrylcholinesterase (BChE)

Catalogue Number: 135-10
Product Name Butyrylcholinesterase
Source Human Serum
Catalogue Number 135-10
Purity Highly Purified
Form Lyophilized
Activity Reported in units/vial (Siemens Dimension® Clinical Chemistry System)
Unit Definition One unit will catalyze the hydrolysis of one micromole of butyrylthiocholine to thiocholine and butyrate per minute at 37°C.
Protein Reported in mg protein/vial (A280, E0.1%=1.6)
Specific Activity > 100 U/mg protein
Appearance White to off-white powder
Reconstitution Use of a phosphate buffer, pH >7.0, containing 0.15 M sodium chloride is recommended.
Formulation Lyophilized from 0.02 M ammonium bicarbonate.
Related Products 135-10 - Butyrylcholinesterase from human serum
343-10 - Esterase from porcine liver
Storage 2-8°C
Recertification 4 years
CAS Number 9001-08-5
E.C. Number
Protein Form Tetrameric glycoprotein
Synonyms BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acylhydrolase, Butyrylcholine esterase, Choline esterase II
Gene BCHE, CHE1, CHE2, E1
Gene ID 590
Accession No P06276
Reaction An acylcholine + H2O = choline + a carboxylate
References C. M. González Tanarro & M. Gütschow (2010) Hyperbolic mixed-type inhibition of acetylcholinesterase by tetracyclic thienopyrimidines, Journal of Enzyme Inhibition and Medicinal Chemistry, 26:3, 350-358.

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