Eosinophil Peroxidase (EPO)

Catalogue Number: 342-60
Description
Product Name Eosinophil Peroxidase
Source Human Eosinophils
Catalogue Number 342-60
Purity > 98% (SDS-PAGE)
Form Liquid
Protein 0.5 - 1.5 mg protein/mL (Coomassie)
Activity > 1,000 U/mL (Enzymatic)
Unit Definition One unit of eosinophil peroxidase will catalyze the consumption of one micromole of hydrogen peroxide and the production of ¼ micromole of tetraguaiacol per minute at pH 7.0 and 25°C.
Specific Activity > 1,000 U/mg protein
Rz Value > 0.8 (A415/A280)
Formulation 0.2 micron filtered solution in 0.1 M sodium phosphate with 0.4 M sodium chloride, pH 7.5.
Appearance Clear, green to brown liquid
Related Products 342-49 - Human NGAL antigen
342-49R - Recombinant human NGAL antigen
426-10 - MPO antigen
Recertification 2 years
Storage 2-8°C
Synonyms EPO
Molecular Weight 77 kda (~53,000 mw heavy chain, ~13,000 mw light chain)
CAS Number 9003-99-0
E.C. Number 1.11.1.7
Gene EPX
Accession No P11678
References British Journal of Pharmacology (2008) 154, 1308–1317
Overview

Lee Biosolutions is the leading supplier of Human Eosinophil Peroxidase (EPO) for medical research and clinical diagnostic manufacturing.

Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.

Our observations show human Eosinophil peroxidase (EPO), is a dimer consisting of both heavy and light chain.

Human Eosinophil peroxidase is a secreted hemoprotein that catalyzes oxidations of various substrates by hydrogen peroxide. Together with other leukocyte-derived enzymes, such as Myeloperoxidase, it plays an important role in the pathogenesis of asthma by mediating oxidative events that lead to the production of ROS (reactive oxygen species) and RNS (reactive nitrogen species).

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SKU PRICE (USD) UNIT QTY
342-60-10 Inquire 10 mg
Representative SDS-PAGE - 342-60