Beta-2 Microglobulin (B2M), Monoclonal Antibody

Catalogue Number: 126-11-4E12
Product Name Mouse Beta-2 Microglobulin (B2M) Monoclonal Antibody
Source Host Mouse
Catalogue Number 126-11-4E12
Form Liquid
Source Monoclonal
Protein 1.0 mg/mL
Form Liquid in phosphate buffered saline, pH 7.2
Clone 4E12
Storage -20°C
Application ELISA
Isotype IgG2a, kappa
Accession No 567

Lee Biosolutions offers research and bulk quantities of anti-Human Beta-2 Microglobulin Antibodies.

Custom preparations, technical support, bulk quantities and aliquoting available, email for more details.

Related Diseases: Carpal tunnel syndrome, hemodialysis-related amyloidosis, diabetes, multiple myeloma

Serum beta-2-Microglobulin, an endogenous marker for renal function, has been shown to be an independent predictor of mortality in older adults. Other applications: In vitro extension of amyloid fibrils, High qualified antigen for antibody production. The beta-2 Microglobulin Class I MHC molecules consist of two separate polypeptide chains. The class I alpha chain is an MHC-encoded, transmembrane polypeptide containing three extracellular domains as referred to alpha1, alpha2, and alpha3. The second polypeptide chain is a non-MHC-encoded, 12 kDa polypeptide called beta-2-microglobulin. Since beta-2-microglobulin (B2M) does not contain a transmembrane domain, it associates with a chain through non-covalent interaction. This interaction is important for the stability of the MHC class I structure, its peptide-loading and its ability to present peptide antigen to CD8+ T cells.

126-11-4E12-0.1 $ 288.00 100 ug
126-11-4E12-0.25 $ 684.00 250 ug
126-11-4E12-1 Inquire 1 mg