Alanine Aminotransferase (ALT/GPT)
| Product Name | Alanine Aminotransferase |
| Source | Human Liver |
| Catalogue Number | 310-19 |
| Purity | Purified |
| Form | Lyophilized |
| Activity | > 5 U/mg (Dimension® Clinical Chemistry System) |
| Unit Definition | One unit will catalyze the transamination of one micromole per minute of L-alanine to α- ketoglutarate, forming L-glutamate and pyruvate, at 37°C and pH 7.4. |
| Protein | > 0.5 mg protein/mg (Coomassie) |
| Specific Activity | > 10 U/mg protein |
| Contaminants | ALP: < 0.1% CK: < 0.1% gGT: < 0.1% AST/SGOT: < 3% LDH: < 1% |
| Formulation | Lyophilized from tris-chloride, EDTA, DTT, α-ketoglutarate, pyridoxal-5-phosphate, pH 7.5. |
| Solubility | Clear, colorless to yellow-green solution (1 mg/mL saline) |
| Recertification | 3 years |
| Storage | -20°C |
| Synonyms | Glutamate Pyruvate Transaminase, Alanine Transaminase, serum glutamic-pyruvic transaminase, SGPT, GPT, ALT, ALAT |
| Additional Info | Homodimer |
| Product Specificity | Liver damage or disease |
| Molecular Weight | 57,903.6 based on the sequence (accession number Q8TD30) |
| CAS Number | 9000-86-6 |
| E.C. Number | 2.6.1.2 |
Lee Biosolutiions is the leading producer of Alanine Aminotransferase (ALT, GPT), Human Liver for research and diagnostic use. We are able to custom fill alanine aminotransferase.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Human GPT/ALT is an enzyme that catalyzes the reversible transfer of an amino group from alanine to a-ketoglutarate. Human alanine aminotransferase (ALT) is found in serum and in various bodily tissues but is most commonly associated with the liver. Also called serum glutamate pyruvate transaminase (SGPT) or alanine aminotransferase.
Elevated levels of Alanine transaminase (ALT) often suggest the existence of other medical problems such as alcoholism, viral hepatitis, congestive heart failure, liver damage, biliary duct problems, infectious mononucleosis, or myopathy.
Lee Biosolutions, Inc
