Gamma-Glutamyl Transferase (gGT)

Catalogue Number: 320-20
Product Name gamma-Glutamyl Transferase
Source Human Liver
Catalogue Number 320-20
Purity Purified
Form Lyophilized
Activity > 1 U/mg (Dimension® Clinical Chemistry System)
Unit Definition One unit will catalyze the transfer of one micromole of the glutamyl moiety from gamma-glutamyl-3-carboxy-4-nitranilide to glycylglycine per minute at 37°C
Protein > 0.1 mg protein/mg (Coomassie)
Specific Activity > 5 U/mg protein
Contaminants ALP: < 5% (Dimension® Clinical Chemistry System)
AST/SGOT: < 5%
Ammonia: < 0.1 micromole/mg
Formulation Lyophilized from 50 mM tris chloride, 1 mM magnesium chloride, 0.2 mM zinc chloride.
Appearance White to brown powder
Storage -20°C
Recertification 3 years
Product Specificity Liver damage or disease
Synonyms Gamma-Glutamyltranspeptidase, Gamma-Glutamyl Transpeptidase, gGT, gamma-GT, GGTP
UNSPSC code 51131907
CAS Number 9046-27-9
E.C. Number

Lee Biosolutions is the leading manufacturer of human gamma Glutamyltransferase/gamma-Glutamyl Transpeptidase (gGT/GGTP). Bulk quantities are available from 50,000 unit single lot sizes.

Custom preparations, technical support, bulk quantities and aliquoting available, email for more details.

Clinical Significance: Detection of liver disease, obstructive jaundice, cholangitis, infectious hepititus, and cholecystitis. gamma-Glutamyltransferase (gGT/GGTP) test is used to detect diseases of the liver, bile ducts, and kidney; and to differentiate liver or bile duct (hepatobiliary) disorders from bone disease.

The liver stores fuel from food, makes proteins, helps remove poisons and toxins, and produces bile, a digestive fluid that helps the body absorb fat. The gallbladder stores bile until it's needed.

Testing for GGT evaluates diseases of the liver, gallbladder, and bile ducts (tubes that carry bile from the liver to the gallbladder and intestine). It also can be used to check for liver damage related to ingestion of toxic substances or alcohol abuse.

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