beta-Nicotinamide-Adenine Dinucleotide (NAD+), Oxidized Form - Free Acid
Product Name | beta-Nicotinamide-Adenine Dinucleotide, Oxidized Form - Free Acid |
Source | Yeast |
Catalogue Number | 940-50 |
Purity | > 95% (Enzymatic) |
Form | Powder |
Moisture Content | < 8% (Karl Fischer) |
Recertification | Reported |
Storage | -20°C |
Synonyms | beta-NAD+, b-DPN+, Coenzyme-I |
Formula | C21H27N7O14P2 |
Formula Weight | 663.4 (As anhydrous free acid) 681.4 (as monohydrate) |
CAS Number | 53-84-9 |
beta NAD Nicotinamide-Adenine Dinucleotide, Oxidized Form available in KG quantities.
Nicotinamide adenine dinucleotide, abbreviated NAD+, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups: with one nucleotide containing an adenine base, and the other containing nicotinamide.
UV Spectral Analysis: Ratios at pH 7.5 A250/A260 (0.83 ± 0.03) A280/A260 (0.21 ± 0.02) å at 260 nm (18.0 ± 0.5) x 103 Ratios at pH 10 after reduction with ADH* A340/A260 (0.43 ± 0.01) å at 340 nm (6.3 ± 0.2) x 10000
The enzymes that make and use NAD+ and NADH are important in both current pharmacology and the research into future treatments for disease. Drug design and drug development exploits NAD+ in three ways: as a direct target of drugs, by designing enzyme inhibitors or activators based on its structure that change the activity of NAD-dependent enzymes, and by trying to inhibit NAD+ biosynthesis.