Item#: 111-11 ALPHA 2 MACROGLOBULIN (A2M)(AMG) Human
Product Info:
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| Product Name: | ALPHA 2 MACROGLOBULIN (A2M)(AMG) Human |
|---|---|
| Cat. No: | 111-11 |
| Expiration: | 1 year |
| Form: | Lyophilized from 0.02M Tris, 0.15M NaCl |
| Molecular Weight: | 650 000-800 000 |
| Protein: | typically >1 mg/ml (dispensing solution) |
| Purity: | >96% by SDS-Page |
| Source: | Human Serum |
| Storage: | 2-8 C |
| Storage: | A2M |
| Synonyms: | Alpha-2-M, A2M, AMG |
| UNSPSC code: | 51131909 |
HUMAN ALPHA 2 MACROGLOBULIN (A2M) BULK QUANTITIES from 100mg to 2000mg single lot sizes. Human Alpha-2-macroglobulin (A2M) custom fills available. Custom buffers on bulk quantities for Human Alpha-2-macroglobulin (A2M).
Recommended dispensing solution of Human Alpha-2-macroglobulin (A2M): 0.05M phosphate buffer pH >7.0 containing 0.15M NaCl
What is Human Alpha 2 Microglobulin?
Human Alpha-2-macroglobulin(A2M)is a large plasma protein found in the blood. Human Alpha-2-macroglobulin (A2M) is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis.
Human Alpha-2-macroglobulin(A2M)levels are increased in nephrotic syndrome, a condition wherein the kidneys start to leak out some of the smaller blood proteins.
Human Alpha-2-macroglobulin (A2M) research: Human Alpha-2-macroglobulin (A2M) is a protease inhibitor and cytokine transporter. Human Alpha-2-macroglobulin (A2M) inhibits many proteases, including trypsin, thrombin and collagenase. Human Alpha-2-macroglobulin (A2M)is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. Human Alpha-2-macroglobulin (A2M) Ref. Nat Genet. 1998 Aug;19(4):357-60/human/a2m/alpha/macroglobulin/polyclonal/antibody
Human Alpha-2-macroglobulin (A2M) research: Activated alpha(2)-macroglobulin induces cell proliferation and mitogen-activated protein kinase activation by LRP-1 in the J774 macrophage-derived cell line. Human Alpha-2-macroglobulin (A2M) REF: Arch Biochem Biophys. 2007 Apr 1;460(1):100-106/human/a2m/alpha/macroglobulin/polyclonal/antibody
Human Alpha-2-macroglobulin (A2M) research: Incorporation of low molecular weight molecules into alpha(2)-Macroglobulin by nucleophilic exchange. Human Alpha-2-macroglobulin (A2M)REF: Biochem Biophys Res Commun. 2007 Jun 1;357(2):433-8/human/a2m/alpha/macroglobulin
Human Alpha-2-macroglobulin (A2M) research:Functional duplication of ligand-binding domains within low-density lipoprotein receptor-related protein for interaction with receptor associated protein, alpha 2-macroglobulin, factor IXa and factor VIII. Human Alpha-2-macroglobulin (A2M) resf: Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, Volume 1774, Issue 6, June 2007, Pages 714-722/human/a2m/alpha/macroglobulin
Human Alpha-2-macroglobulin (A2M) research:Activated alpha2-macroglobulin induces cell proliferation and mitogen-activated protein kinase activation by LRP-1 in the J774 macrophage-derived cell line.Human Alpha-2-macroglobulin (A2M) ref:Archives of Biochemistry and Biophysics, Volume 460, Issue 1, 1 April 2007, Pages 100-106//human/a2m/alpha/macroglobulin
Human Alpha-2-macroglobulin (A2M) research:Roles for C3 and alpha-2 macroglobulin in the transportation and activation of MASP-2 in normal human serum.Human Alpha-2-macroglobulin (A2M) ref:Molecular Immunology, Volume 44, Issues 1-3, January 2007, Page 15/human/a2m/alpha/macroglobulin