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Human RECOMBINANT Type II CREATINE KINASE MB ISOENZYME (CKMB) - Cardiac BioMarker

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Item #: 191-26R2

Description

Expiration:

1 year

Form:

50% Glycerol, Tris Buffer, pH 6.3-7.2

Synonyms:

r-hCKMB II, r-hCK-MB, r-hCK-2

Source:

Pichia Pastoris

Activity:

Typically >400 u/ml @ 37C

Cat. No:

191-26R2

Protein:

Typically >5 mg/ml

Purity:

>90% by Capillary Electrophoresis

Storage:

-70C

Price

Unit

Qty

$450.00

mg

$150.00

250ug

Details

RECOMBINANT CREATINE KINASE MB isoenzyme, CK-MB Isoenzyme BULK QUANTITIES from 50-500 mg single lot sizes.

Human Creatine Kinase (CPK)CK Unit Definition: One unit will transfer one umole of phosphate from Creatine Phosphate to ADP per minute at 37C. Measured at 340 nm as one equimolar amount of NADH produced by a coupled reaction.

Recombinant full length Creatine Kinase MB Isoenzyme with amino acid sequence exactly the same as the native enzyme. Purified in the enzymatically active form. Reacts with monoclonal antibodies specific to MB isoenzyme in ELISA. CKMB is a 47 kDa dimeric protein comprised of the M and B subunits, produced in Pichia pastoris, and purified under non-denaturing conditions.

Human isoenzyme creatine kinase MB CKMB, CK-MB (CPK-2) isoenyzme is used due to its ability to detect reinfarction. Human creatine kinase CKMB isoenyzme used to be the gold standard for myocardial necrosis.

Human creatine kinase MB CKMB(CPK-MB)isoenzyme (also called CPK-2 isoenzyme) is found mostly in the heart.

Human creatine kinase CKMB,CK-MB isoenzyme(CPK-2)is one of the most important myocardial markers (in spite of not being altogether cardiac-specific), with well-established roles in confirming acute myocardial infarction (AMI). Human creatine kinase CK-MB CKMB isoenzyme is also used for monitoring reperfusion during thrombolytic therapy following AMI.

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