Item#: 431-11 MYOGLOBIN, Human (Mb)

Human heart MYOGLOBIN(Mb)protein from 100-5000mg single lot sizes. Custom buffers for human heart myoglobin available. Custom fills of human heart myoglobin available.

Myoglobin related products that we offer:
431-11R Recombinant Human Myoglobin
431-11 Native Human Myoglobin
CMY-80A Polyclonal chicken anti-myoglobin affinity purified
SMY-80A Polyclonal sheep anti-human myoglobin affinity purified

HUMAN MYOGLOBIN:
Human Myoglobin is a single-chain globular protein of 153 amino acids. Myoglobin contains a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. Human Myoglobin has a molecular weight of 16,700 daltons. Human Myoglobin is found in skeletal and cardiac muscle cells and is capable of reversibly binding molecular oxygen and enhancing the rate of oxygen diffusion through the muscle cell. Human Myoglobin is an oxygen carrier in the cytoplasm and appears to be responsible for the transport of oxygen from the cell membrane to the mitochondrion.
Human cardiac Myoglobin (Mb) is a Haem containing protein and implicated as a cause of acute renal failure following damage to muscle tissue (e.g. rhabdomyolysis, severe crush trauma, malignant hyperthermia, status epilepticus and neuroleptic malignant syndrome), due to its toxicity to renal tubular epithelium. Human Myoglobin also serves as a useful biomarker for the detection of successful reperfusion following thrombolytic therapy