HUMAN PROSTATIC ACID PHOSPHATASE

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Item #: 475-31

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Lee Biosolutions produces human PROSTATIC ACID PHOSPHATASE ENZYME(PAP,ACP) for research and bulk IVD diagnostic manufacturing. LeeBio has an extensive human semen donor program. Custom Acid Phosphatase purification on donor specific semen is available. As a producer we can modify buffer and do custom fills of human prostatic acid phosphatase

Human Prostate Acid Phosphatase also known as human prostatic acid phosphatase(PAP,ACP) is alternative marker to prostate specific antigen (PSA) for prostate malignancy. Rape investigations will often include testing for the presence of Human prostatic (prostate) acid phosphatase in vaginal fluid.

Human prostatic Acid phosphatase (PAP)is a phosphatase, a type of enzyme, used to free attached phosphate groups from other molecules during digestion. Acid Phosphatase is stored in lysosomes and functions when these fuse with endosomes, which are acidified while they function; therefore,Human Acid Phosphatase has an acid pH optimum below 7.0.

Current Research by Expert Rev Anticancer Ther. 2010 Jul;10(7):1055-68. Prostatic acid phosphatase (PAP) is the most abundant phosphatase in human prostate tissue/secretions. It is a clinically important protein for its relevance as a biomarker of prostate carcinoma. Furthermore, it has a potential role in fertilization. We describe here most of the features of PAP including gene regulation, gene/protein structure, functions, its role in tumor progression and evolutionary features. PAP has phosphatase activity and is an extensively studied biomarker of prostate cancer. The major action of PAP is to dephosphorylate macromolecules with the help of catalytic residues (His(12) and Asp(258)) that are located in the cleft between two domains. This article will be of great interest to all those scientists who are working in the area of prostate pathophysiology

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