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Human Skeletal Muscle CREATINE KINASE MM ISOENYZME (CKMM)

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Item #: 190-29

Description

Cat. No:

190-29

CK Electrophoresis:

100% CKMM, no CKBB or CKMB detected

Purity:

>96% by SDS Page

Activity:

Typically >1000 u/ml @ 37C

Product Name:

CKMM ISOENZYME

Form:

50% Glycerol,50mM Tris, 2mM DTT at pH 7.5

Expiration:

1 year

UNSPSC code:

51131907

Source:

Human Skeletal Muscle

Storage:

-20C long term 2-8 C short term

Price

Unit

Qty

$300.00

500ug

$100.00

50ug

Details

CREATINE KINASE MM ISOENZYME CKMM(CK-MM) isoenzyme available in BULK QUANTITIES from 10-500 mg single lot sizes. LeeBio is a major bulk manufacturer of cardiac markers and can supply in buffer of your choice.

Human (CK-MM)CKMM isoenzyme also known as human CPK-3 isoenzyme is normally responsible for almost all human (CK)CPK enzyme activity in healthy people. When human (CK-MM)CKMM isoenzyme is elevated, this usually indicates injury or stress to skeletal muscle

Background: Human Creatine phosphokinase (CK)CPK isoenzymes are performed when the total human CPK level is elevated. Human CK(CPK)Isoenzyme testing can help differentiate the source of the damaged tissue. Human (CPK)CK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Human (CKMM)CK-MM, Human (CKBB)CK-BB isoenzyme and Human (CKMB)CK-MB isoenzyme exist.

Human (CKBB)CK-BB isoenzyme occurs mainly in brain and lung tissues. Skeletal muscle expresses Human (CKMM)CK-MM isoenzyme(98%) and human (CKMB)CK-MB isoenzyme at low levels (1%) in muscle. The myocardium (heart muscle), in contrast, expresses human (CKMM)CK-MM isoenzyme at 70% and human (CKMB)CK-MB isoenzyme at 30%.

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