We Are Solutions...On Demand
Item #: 342-40
> 96% (SDS-PAGE, confirmed via Western Blot)
Typically > 1.0 mg/mL (Coomassie)
Neutrophil Elastase - Grade II
Typically > 50 U/mL @ 37C
IN STOCK - Ships same day
One unit will hydrolyze one micromole of methoxy succinyl-alanine-alanine-proline-valine-p-nitroanilide per minute at 37C and pH 7.5.
0.05 M sodium acetate, 0.6 M sodium chloride, pH 5.5
ELA-2, Elastase, hne, leukocyte elastase, serine elastase, elaszym
> 25 U/mg protein
Lee Biosolutions is the leading producer of human neutrophil Elastase (NEG) for clinical research, life science and diagnostic manufacturing uses.
Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Related Products Offered:
186-10 Human Neutrophil Cathepsin G
497-50 Human Neutrophil Proteinase 3 (PR3)
426-10 Human Neutrophil Myeloperoxidase (MPO)
Human Neutrophils, also known as neutrophilic polymorphonuclear leukocytes, are the major class of white blood cell in human peripheral blood. They, have a multilobed nucleus and neutrophilic granules, and are phagocytes and have an important role in engulfing and killing extracellular pathogens.
The neutrophil form of elastase is 218 amino acids long, with two asparagine-linked carbohydrate chains. Current studies show that both Cathepsin G and Neutrophil Elastase are key enzymes for tissue injury caused by activated neutrophils, such as occurs in Acute Lung injury