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Myoglobin (Mb)

Catalogue Number: 431-11
Availability: In Stock

Description

Product Name Myoglobin
Source Human Heart
Catalogue Number 431-11
Purity > 99% (SDS-PAGE)
Form Liquid
Protein 2.0 - 4.0 mg/mL (Lowry)
Form Solution in phosphate buffered saline, pH 7.5 with 0.09% sodium azide.
Appearance Clear, reddish-brown solution
Storage 2-8°C
Recertification 3 years
Molecular Weight Approx. 16.7 - 17.7 kDa
UNSPSC code 51131907
CAS Number 11080-17-4
Gene MB, RP4-569D19.7, PVALB, myoglobgin
Gene ID 4151
Accession No P02144
SKUPRICEUNITQTY
431-11-1 $ 85.00 1 mg
431-11-5 $ 275.00 5 x 1 mg
431-11-10 $ 500.00 10 mg
431-11-100 Inquire 100 mg
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Lee Biosolutions produces human cardiac Myoglobin for research and manufacturing uses.

Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details. Single lot sizes from 1,000 - 5,000 mg.

This product is a single-chain globular protein of 153 amino acids and contains a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds.

Myoglobin is found in skeletal and cardiac muscle cells and is capable of reversibly binding molecular oxygen and enhancing the rate of oxygen diffusion through the muscle cell. Human Myoglobin is an oxygen carrier in the cytoplasm and appears to be responsible for the transport of oxygen from the cell membrane to the mitochondrion.

Myoglobin (Mb) is implicated as a cause of acute renal failure following damage to muscle tissue (e.g. rhabdomyolysis, severe crush trauma, malignant hyperthermia, status epilepticus and neuroleptic malignant syndrome), due to its toxicity to renal tubular epithelium.

Diagnostic Controls, Calibrators & Standards

Immunoassays

Antibody Production

Clinical Chemistry

Testing/Assay Validation

Life Science

ELISA, Blotting, Etc.

Characterization

Validation Studies

Cardiac Markers

Urinalysis

Manufacturing

Immunization

These items are purified for use as an antigen/immunogen for antibody production.